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Enhancing existing approaches to peripheral T|cell lymphoma


Enhancing existing approaches to peripheral T-cell lymphoma

Outcomes with conventional therapies, many of which are borrowed from B-cell lymphoma, are poor. Strategies to enhance existing approaches include creating a ...

Enhancing Existing Approaches to Peripheral T-Cell Lymphoma

Strategies to enhance existing approaches include creating a new platform for first-line therapy and adding novel agents, such as denileukin diftitox, to ...

Strategies for Relapsed Peripheral T-Cell Lymphoma: The Tail That ...

For those with primary refractory or relapsed PTCL, the optimal approach to management is unclear, and data regarding the outcome for these patients is limited.

Current and upcoming treatment approaches to common subtypes ...

The treatment of common nodal peripheral T-cell lymphomas (PTCLs), including PTCL, not otherwise specified (PTCL, NOS), ...

Enhancing Existing Approaches to Peripheral T-Cell Lymphoma ...

Request PDF | Enhancing Existing Approaches to Peripheral T-Cell Lymphoma | The National Comprehensive Cancer Network (NCCN) practice guidelines for ...

Past, present and future therapeutic approaches in nodal peripheral ...

Peripheral T-cell lymphomas (PTCL) encompass over 30 different entities and although they share post-thymic T- or NK-cell derivation, ...

T time: Emerging and new therapies for peripheral T-cell lymphoma

Peripheral T-cell Lymphomas (PTCL) are a heterogenous group of aggressive non-Hodgkin lymphomas that are far less sensitive to chemotherapy than their ...

How I treat the peripheral T-cell lymphomas | Blood - ASH Publications

Based on the best data currently available, which include retrospective analyses and phase 2 prospective studies, our approach has involved cyclophosphamide, ...

Peripheral T-Cell Lymphomas: Therapeutic Approaches - MDPI

Peripheral T-cell lymphomas are a group of rare cancers of T cells or natural killer cells, most often with a poor prognosis.

Peripheral T-Cell Non-Hodgkin Lymphoma Treatment (PDQ®) - NCI

Peripheral T-cell non-Hodgkin lymphoma treatment options include chemotherapy, radiation, targeted therapy, stem cell transplant, ...

Frontline Management of Nodal Peripheral T-Cell Lymphomas

Cyclophosphamide, doxorubicin, prednisone, and brentuximab vedotin CHP-BV is the first therapy in PTCL to show an overall survival benefit and ...

Current Treatment of Peripheral T-cell Lymphoma - Cancer Network

Valemetostat, a potent oral dual inhibitor of enhancer of zeste homologue (EZH) 1 and 2, has broad activity against B-cell lymphomas and TCLs, ...

Emerging predictive biomarkers for novel therapeutics in peripheral ...

Bortezomib monotherapy has been trialed in the setting of cutaneous T cell lymphoma with an ORR of 67% (147), as well as in numerous combination therapy ...

Precise diagnosis and treatment for peripheral T-cell lymphomas

Unraveling the intricate pathogenic mechanisms underlying PTCLs is pivotal for the development of targeted therapies, which has become a major focus of PTCL ...

The peripheral T-cell lymphomas: an unusual path to cure

Decades of effort have focused on retrofitting chemotherapy programmes used for other diseases, such as CHOP (cyclophosphamide, doxorubicin, vincristine, and ...

Newly Approved Drug Combination Improves Survival for People ...

People newly diagnosed with peripheral T cell lymphoma have traditionally been treated with chemotherapy. A recent study showed that adding a ...

Peripheral T-Cell Lymphoma

Cutaneous T-cell lymphomas consist of a number of different diseases with various signs and symptoms, treatment approaches and outcomes. For specific ...

Changing the Paradigms of Treatment in Peripheral T-cell Lymphoma

Despite enormous advances in our understanding of aggressive lymphomas, it is clear that progress in the peripheral T-cell lymphomas (PTCL) ...

Pathobiology of nodal peripheral T-cell lymphomas - Haematologica

The main adjustments and changes introduced in both proposals reflect similar conceptual shifts. Here, we present a review of our current knowledge of the ...

Targeted Approaches to T-Cell Lymphoma - MDPI

They are subdivided into the Peripheral T-cell lymphomas (PTCL) and the Cutaneous T-cell lymphomas (CTCL). The PTCLs are characteristically aggressive and ...