Epidermal growth factor receptor

Epidermal growth factor receptor - Wikipedia

Epidermal growth factor receptor ... The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members ...

Definition of epidermal growth factor receptor - NCI Dictionary of ...

epidermal growth factor receptor ... A protein found on certain types of cells that binds to a substance called epidermal growth factor. The epidermal growth ...

Biochemistry, Epidermal Growth Factor Receptor - StatPearls - NCBI

The epidermal growth factor receptor (EGFR) family is a subclass of receptor tyrosine kinase (RTK) proteins and consists of 4 members: EGFR ...

Gene ResultEGFR epidermal growth factor receptor [ (human)] - NCBI

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members ...

EGFR gene: MedlinePlus Genetics

The EGFR gene provides instructions for making a receptor protein called the epidermal growth factor receptor, which spans the cell membrane ...

Revisiting Epidermal Growth Factor Receptor (EGFR) Amplification ...

We investigated the genomic landscape of EGFR amplification in blood-derived cell-free tumor DNA (cfDNA) across diverse cancers and the role of anti-EGFR ...

Epidermal Growth Factor Receptor - an overview - ScienceDirect.com

The epidermal growth factor receptor (EGFR) regulates many tumor-promoting processes such as growth, survival, and migration. Some tumors, such as certain lung ...

Epidermal growth factor receptor (EGFR) and EGFR mutations ...

EGFR is a growth factor receptor that induces cell differentiation and proliferation upon activation through the binding of one of its ligands.

EGFR - Epidermal growth factor receptor - Homo sapiens (Human)

Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular ...

Epidermal growth factor receptor mutations in lung cancer - Nature

We review the results of genetic, biochemical and clinical studies focused on somatic mutations of EGFR that are associated with the phenomenon of oncogene ...

Epidermal Growth Factor Receptor - an overview - ScienceDirect.com

The epidermal growth factor receptors (EGFR) are transmembrane receptors from receptor tyrosine kinase superfamily. Upon binding an extracellular ligand to EGFR ...

The Epidermal Growth Factor Receptor Pathway: A Model for ...

EGFR becomes activated by receptor overexpression (frequent in cancer) as well as ligand-dependent and ligand-independent mechanisms. There are ...

Human epidermal growth factor receptor 2 - National Cancer Institute

Human epidermal growth factor receptor 2 may be made in larger than normal amounts by some types of cancer cells, including breast, ovarian, bladder, pancreatic ...

Type I RTKs: ErbB (epidermal growth factor) receptor family

The IUPHAR/BPS Guide to Pharmacology. epidermal growth factor receptor - Type I RTKs: ErbB (epidermal growth factor) receptor family.

Activating Mutations in the Epidermal Growth Factor Receptor ...

Conclusions. A subgroup of patients with non–small-cell lung cancer have specific mutations in the EGFR gene, which correlate with clinical responsiveness to ...

EGFR and Lung Cancer | American Lung Association

Errors in the EGFR gene are one type of lung cancer biomarker. EGFR, which stands for epidermal growth factor receptor, is a protein located on ...

EGFR Gene - GeneCards | EGFR Protein | EGFR Antibody

EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell ...

Epidermal growth factor receptor (EGFR) is a target of the ... - PNAS

FBXW7 is an E3 ubiquitin ligase that targets proteins for proteasome-mediated degradation and is mutated in various cancer types.

Review of epidermal growth factor receptor biology

Although present in normal cells, EGFR is overexpressed in a variety of tumor cell lines and has been associated with poor prognosis and decreased survival.

Epidermal Growth Factor Receptors (EGFRs) - Sino Biological

Epidermal Growth Factor Receptor Overview. Epidermal growth factor receptor (EGF receptor) belongs to the ErbB family of receptor tyrosine kinases (RTK). EGF ...