Epigenetic foundations of pluripotent stem cells that recapitulate in ...

In mammalian development, dynamic epigenetic reprogramming occurs in pre-implantation embryos and primordial germ cells and plays a critical role in ...

In mammalian development, dynamic epigenetic reprogramming occurs in pre-implantation embryos and primordial germ cells and plays a critical ...

Epigenetic foundations of pluripotent stem cells that recapitulate in ...

Request PDF | Epigenetic foundations of pluripotent stem cells that recapitulate in vivo pluripotency | In mammalian development, dynamic epigenetic ...

Special Issue: Cancer stem cells and pluripotent/multipotent stem cells

Epigenetic foundations of pluripotent stem cells that recapitulate in vivo pluripotency. Masaki Yagi; Shinya Yamanaka; Yasuhiro Yamada. Pathobiology in Focus 4 ...

Epigenetics of reprogramming to induced pluripotency - PMC

Reprogramming to induced pluripotent stem cells (iPSCs) proceeds in a step-wise manner with reprogramming factor binding, transcription, and chromatin ...

Epigenetic aberrations in human pluripotent stem cells - EMBO Press

These results suggest a special role for imprinted genes in regulating stem cell properties, therefore supporting the speculation that LOI might ...

Epigenetic Regulation of Transition Among Different Pluripotent ...

Although diverse pluripotent stem cell cultures all have the ability to differentiate into all the three germ layers and can self-renew, it has ...

Human Induced Pluripotent Stem Cells: From Cell Origin, Genomic ...

On the other hand, reprogramming of somatic cells to iPSCs requires profound modifications in the epigenetic landscape. Changes in chromatin structure by DNA ...

Epigenetic resetting of human pluripotency | Development

Much attention has focussed on the conversion of human pluripotent stem cells (PSCs) to a more naïve developmental status. Here we provide a method for ...

Source cell-type epigenetic memory persists in induced pluripotent ...

Introduction: Retention of source cell-type epigenetic memory may mitigate the potential for induced pluripotent stem cells (iPSCs) to fully achieve ...

Epigenetic Modification Factors and microRNAs Network Associated ...

[19]. The second technique for differentiating pluripotent stem cells into cardiomyocytes uses embryoid bodies in suspension. The pluripotent stem cells begin ...

Epigenetic dynamics during capacitation of naïve human pluripotent ...

Human pluripotent stem cells (hPSCs) are of fundamental relevance in regenerative medicine. Naïve hPSCs hold promise to overcome some of the ...

Genetic and Epigenetic Regulators of Pluripotency | Semantic Scholar

Epigenetic foundations of pluripotent stem cells that recapitulate in vivo pluripotency · Masaki YagiS. YamanakaYasuhiro Yamada. Biology, Medicine. Laboratory ...

Epigenetic Memory: Lessons From iPS Cells Derived From Human β ...

Incomplete reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) may be responsible for the heterogeneity in differentiation capacity ...

Cellular reprogramming and epigenetic rejuvenation

Since the creation of induced pluripotent stem cells (iPSCs) in vitro, it has become clear that cellular identity is dictated by epigenetic ...

Epigenetic Alterations in Human Pluripotent Stem Cells: A Tale of ...

Human somatic cells can be reprogrammed into induced pluripotent stem cells (hiPSCs) with wide lineage differentiation potential in culture.

Returning to the stem state: Epigenetics of recapitulating pre ...

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can self-renew indefinitely and contribute to all tissue types of the ...

PSC Epigenetic Landscape | Cell Quality - STEMCELL Technologies

Epigenetic Landscape of Pluripotent Stem Cells ... Epigenetic regulation occurs in multiple waves during early embryonic development. After fertilization, both ...

Wolf Reik - Publications | Babraham Institute

Human 8-cell embryo-like cells from pluripotent stem cells. Open Access. Taubenschmid-Stowers J, Reik W Epigenetics.

October 2017 - Laboratory Investigation

Epigenetic foundations of pluripotent stem cells that recapitulate in vivo pluripotency. Masaki Yagi,; Shinya Yamanaka,; Yasuhiro Yamada. Published in issue ...