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Estimating genetic nurture with summary statistics of ...


Estimating genetic nurture with summary statistics of ... - PNAS

We propose a statistical framework to estimate direct and indirect genetic effects using summary statistics from GWAS conducted on own and offspring phenotypes.

Estimating genetic nurture with summary statistics of ... - PubMed

We propose a statistical framework to estimate direct and indirect genetic effects using summary statistics from GWAS conducted on own and offspring phenotypes.

Estimating genetic nurture with summary statistics of multi ... - bioRxiv

Here, we propose a novel statistical framework to estimate direct and indirect genetic effects using summary statistics from GWAS conducted on.

Estimating genetic nurture with summary statistics of ... - NASA ADS

Estimating genetic nurture with summary statistics of multigenerational genome-wide association studies ... Abstract. It has been shown that human genomes can ...

Estimating genetic nurture with summary statistics of ... - Scite

Here, we propose a statistical framework to estimate direct and indirect genetic effects using summary statistics from GWAS conducted on own and offspring ...

Estimating genetic nurture with summary statistics of ...

Here, we propose a statistical framework to estimate direct and indirect genetic effects using summary statistics from GWAS conducted on own and offspring ...

Yuchang Wu: Estimating genetic nurture using genome ... - YouTube

Yuchang Wu: Estimating genetic nurture using genome-wide association study summary statistics ; Yuexuan Xu: Bald is Beautiful? Life Course ...

Estimating direct and indirect genetic effects on offspring ...

Estimation of direct and indirect (i.e. parental and/or sibling) genetic effects on phenotypes is becoming increasingly important. We compare several ...

Summary Statistics - Lu Laboratory

Reference: Wu et al. (2021). Estimating genetic nurture with summary statistics of multi-generational genome-wide association studies. Proceedings of the ...

bioRxiv on X: "Estimating genetic nurture with summary statistics of ...

Estimating genetic nurture with summary statistics of multi-generational genome-wide association studies https://t.co/vUfwkbbBmW #bioRxiv.

Statistical methods for SNP heritability estimation and partition

A key quantity to evaluate the contribution of genetics versus environment is heritability, which measures the proportion of phenotypic variance explained by ...

The goldmine of GWAS summary statistics: a systematic review of ...

Estimating genetic nurture with summary statistics of multigenerational genome-wide association studies. Proc Natl Acad Sci U S A. 2021;118 ...

Robust genetic nurture effects on education: A systematic review ...

A total of 12 studies comprising 38,654 distinct parent(s)-offspring pairs or trios from 8 cohorts reported 22 estimates of genetic nurture effects. Genetic ...

Assessing the contribution of genetic nurture to refractive error - Nature

We found no evidence of a contribution from genetic nurture: non-within-family SNP-heritability estimate = 0.213 (95% confidence interval 0.134– ...

Preliminary Evidence for Genetic Nurture in Depression and ...

This cross-sectional study used linear mixed modeling of polygenic scores to estimate the association of genetic nurture across a range of ...

Genetic nurture effects on education: a systematic review and meta ...

Fourth, to what extent the estimated genetic nurture effects differ depending on the accuracy of GWAS summary statistics used to derive the PGS ...

Robust genetic nurture effects on education - Cell Press

genome-wide data have enabled the estimation of genetic ... Genetic nurturing, missing heritability, and causal analysis in genetic statistics.

Modeling Parent-Specific Genetic Nurture in Families ... - UQ eSpace

The summary statistics from the analyses of these two distinct datasets are then combined to provide overall estimates of child, paternal and maternal effects.

Estimation of Parental Effects Using Polygenic Scores

The occurrence of genetic nurture has important implications for understanding complex trait genetics. Genetic nurture increases the phenotypic ...