Evaluating the evaluation of cancer driver genes

Evaluating the evaluation of cancer driver genes - PNAS

We present a machine-learning–based method for driver gene prediction and a protocol to evaluate and compare prediction methods.

Evaluating the evaluation of cancer driver genes - PubMed

Sequencing has identified millions of somatic mutations in human cancers, but distinguishing cancer driver genes remains a major challenge.

Evaluating the evaluation of cancer driver genes - PNAS

Sequencing has identified millions of somatic mutations in human cancers, but distinguishing cancer driver genes remains a major challenge.

Evaluating the evaluation of cancer driver genes.

, Evaluating the evaluation of cancer driver genes. ;; Tokheim, Collin J ;, ISSN: 0027-8424 , 1091-6490 ;, Proceedings of the National Academy of Sciences of ...

Evaluating the Evaluation of Cancer Driver Genes | bioRxiv

Key to this effort has been development of computational algorithms to find genes that drive cancer, based on their patterns of mutation in ...

Comprehensive evaluation of computational methods for predicting ...

Cancer genomes are characterized by the accumulation of molecular alterations such as driver and non-driver mutations. Driver mutations have ...

Evaluating the evaluation of cancer driver genes | Request PDF

Request PDF | Evaluating the evaluation of cancer driver genes | Significance Modern large-scale sequencing of human cancers seeks to comprehensively ...

Cancer driver mutations: predictions and reality - Cell Press

Driver mutations are associated with clinical phenotype and can be used as cancer biomarkers. Abstract. Cancer cells accumulate many genetic ...

Evaluating machine learning methodologies for identification of ...

Cancer is driven by distinctive sorts of changes and basic variations in genes. Recognizing cancer driver genes is basic for accurate ...

Evaluating the evaluation of cancer driver genes - Ex Libris

Sequencing has identified millions of somatic mutations in human cancers, but distinguishing cancer driver genes remains a major challenge.

Prediction of cancer driver genes and mutations - Oxford Academic

To date, many computational tools and frameworks have been presented to predict driver genes, driver mutations, and the structural impact of ...

A network-based method for identifying cancer driver genes ... - NCBI

The cancer genes in CGC are used as the gold standard to assess the performance of each method according to the predicted cancer drivers. The more the driver ...

Current cancer driver variant predictors learn to recognize driver ...

The first is to define the positive samples as recurrent variants that map to curated sets of driver genes (as in [10]), and the second is to ...

Comprehensive Characterization of Cancer Driver Genes and ...

We identify 299 driver genes with implications regarding their anatomical sites and cancer/cell types. Sequence- and structure-based analyses ...

Cancer driver mutations: predictions and reality

that will help to identify and study cancer driver mutations. ... (2016) Evaluating the evaluation of cancer · driver genes. Proc. Natl. Acad ...

Evaluating the evaluation of cancer driver genes - OUCI

Key to this effort has been development of computational algorithms to find genes that drive cancer based on their patterns of mutation in large patient cohorts ...

Ontology-based prediction of cancer driver genes | Scientific Reports

Due to inter-tumor genetic heterogeneity many driver mutations within a gene occur at low frequencies, which make it challenging to distinguish ...

deepDriver: Predicting Cancer Driver Genes Based on Somatic ...

With the advances in high-throughput technologies, millions of somatic mutations have been reported in the past decade. Identifying driver ...

CancerGATE: Prediction of cancer-driver genes using graph ...

Recently, graph deep learning methods became widely used in finding cancer-driver genes. However, previous methods had limited performance in ...

Evaluating the evaluation of cancer driver genes - Altmetric

Evaluating the evaluation of cancer driver genes. Overview of attention for article published in Proceedings of the National Academy of Sciences of the ...