Evaluation of 13C isotopic tracers for metabolic flux analysis in ...

(13)C metabolic flux analysis (MFA) is the most comprehensive means of characterizing cellular metabolic states. Uniquely labeled isotopic tracers enable ...

13C metabolic flux analysis (MFA) is the most comprehensive means of characterizing cellular metabolic states. Uniquely labeled isotopic tracers enable more ...

Evaluation of 13C isotopic tracers for metabolic flux analysis in ...

We computationally evaluated specifically labeled 13 C glucose and glutamine tracers for their ability to precisely and accurately estimate fluxes in central ...

Evaluation of 13C isotopic tracers for metabolic flux analysis in ...

Download Citation | Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells | (13)C metabolic flux analysis (MFA) is the most ...

A guide to 13 C metabolic flux analysis for the cancer biologist - Nature

The selection of an isotopic tracer (or multiple tracers) is one of the most important considerations when designing 13C-MFA studies, since this ...

Optimization of 13C isotopic tracers for metabolic flux analysis in ...

▻ The performance of 13C tracers in MFA was scored based on confidence intervals. ▻ Combinations of tracer substrates were optimized using a genetic algorithm.

13 C metabolic flux analysis: Classification and characterization ...

13C metabolic flux analysis (13C-MFA) has emerged as a forceful tool for quantifying in vivo metabolic pathway activity of different biological systems.

Evaluation of 13C isotopic tracers for metabolic flux analysis in ...

Metabolic fluxes in central carbon metabolism (glycolysis, TCA cycle, exchange with amino acids, etc.) are very informative about the state of the cell.

Rational design of 13C-labeling experiments for metabolic flux ...

13C-Metabolic flux analysis (13C-MFA) is a standard technique to probe cellular metabolism and elucidate in vivo metabolic fluxes.

[PDF] Optimization of 13C isotopic tracers for metabolic flux analysis ...

Semantic Scholar extracted view of "Optimization of 13C isotopic tracers for metabolic flux analysis in mammalian cells." by Jason Walther et al.

Evaluation of 13C isotopic tracers for metabolic flux analysis in ...

(13)C metabolic flux analysis (MFA) is the most comprehensive means of characterizing cellular metabolic states. Uniquely labeled isotopic tracers enable more ...

13C metabolic flux analysis: Optimal design of isotopic labeling ...

Traditional methods for selecting isotopic tracers and labeling measurements did not fully utilize the power of 13C-MFA. Recently, new approaches were developed ...

In Vivo Estimates of Liver Metabolic Flux Assessed by 13C ...

Isotope-based assessment of metabolic flux is achieved through a judicious balance of measurements and assumptions.

Metabolic Flux Analysis and In Vivo Isotope Tracing

Versatility and Cost-Effectiveness: 13C-labeled glucose is the most popular in vivo tracer due to its ability to rapidly label many pathways in central carbon ...

Using Multiple Tracers for 13 C Metabolic Flux Analysis

13C-Metabolic flux analysis (13C-MFA) is a powerful technique for quantifying intracellular metabolic fluxes in living cells. These in vivo fluxes provide ...

Optimization of 13C isotopic tracers for metabolic flux analysis in ...

Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry. W. Ahn, M. Antoniewicz.

Global 13C tracing and metabolic flux analysis of intact human liver ...

Perhaps half of all metabolic enzymes encoded in the human genome are still uncharacterized, and non-targeted isotope tracing provides ...

13C Metabolic Flux Analysis - SpringerLink

C MFA is an experimental approach to compute intracellular flux pattern. It involves tracer studies where substrates are labeled with stable isotopes, such as ...

A Guide to 13C Metabolic Flux Analysis for the Cancer Biologist

1 Isotopically Nonstationary 13C Metabolic Flux Analysis in Resting ...

Isotope assisted metabolic flux analysis (13C-MFA) is the current ... Evaluation of 13C isotopic tracers for metabolic flux analysis in ...