Evaluation of drug|drug interaction between rilpivirine and ...

Evaluation of drug-drug interaction between rilpivirine and ... - NCBI

This in silico study investigates the drug-drug interaction (DDI) magnitude between daily oral rilpivirine 25 mg with either daily 600 mg or weekly 900 mg ...

Evaluation of drug-drug interaction between rilpivirine and ... - PubMed

Tuberculosis remains the leading cause of death among people living with HIV. Rifapentine is increasingly used to treat active disease or ...

Evaluation of drug-drug interaction between rilpivirine ... - Frontiers

daily oral rilpivirine 25mg with either daily 600mg or weekly 900mg rifapentine. A physiologically based pharmacokinetic (PBPK) model was built.

Evaluation of drug-drug interaction between rilpivirine ... - Europe PMC

The simulations of concomitant administration of rifapentine with rilpivirine at steady-state lead to a maximum decrease on AUC0-24 and Ctrough by 83% and 92% ...

(PDF) Evaluation of drug-drug interaction between rilpivirine and ...

Conclusions Model predictions suggest that monthly long‐acting cabotegravir could maintain antiviral efficacy throughout pregnancy, but that ...

Evaluation of drug-drug interaction between rilpivirine and ...

Evaluation of drug-drug interaction between rilpivirine and rifapentine using physiologically based pharmacokinetic modelling ; Item Type: ...

Evaluation of drug-drug interaction between rilpivirine and ... - OUCI

The drug-drug interaction model suggested a significant decrease on rilpivirine exposure which is unlikely to be corrected by dose increment, thus ...

Management of Drug-Drug Interactions Between Long-Acting ...

Drug-drug interactions (DDI) between strong inducers and long-acting (LA) cabotegravir and rilpivirine cannot be overcome. However, DDIs with moderate indu.

Pharmacokinetics and Drug–Drug Interactions of Long-Acting ...

However, oral cabotegravir and rilpivirine can be subject to DDIs at the intestinal and hepatic levels. Results from DDI studies between oral ...

Lack of Pharmacokinetic Interaction between Rilpivirine and ...

Long-acting depot injections of GSK1265744 and RPV are also being developed. This study evaluated the potential for drug interactions between RPV and these INIs ...

Drug-Drug Interactions between Antiretrovirals and Other Drugs | NIH

A thorough review of concomitant medications in consultation with an expert in ARV pharmacology can help in designing a regimen that minimizes undesirable ...

British Journal of Clinical Pharmacology - Wiley Online Library

This review aims to consider pharmacokinetic characteristics of cabotegravir and rilpivirine and describe anticipated drug–drug interactions ( ...

ciac901.pdf - Oxford Academic

Management of Drug-Drug Interactions Between. Long-Acting Cabotegravir and Rilpivirine and. Comedications With Inducing Properties: A Modeling Study. Sara ...

Potential of the novel antiretroviral drug rilpivirine to modulate the ...

Drug interactions may compromise the safety and effectiveness of HIV therapy. For rilpivirine, published data on its drug–drug interaction potential are sparse.

Clinical pharmacology considerations and drug–drug interactions ...

This review aims to consider pharmacokinetic characteristics of cabotegravir and rilpivirine and describe anticipated drug–drug interactions (DDIs) with ...

MDR1 and BCRP Transporter-Mediated Drug-Drug Interaction ...

The aim of our study was to evaluate rilpivirine interactions with abacavir and lamivudine on selected ABC and SLC transporters in vitro and assess its ...

208351Orig1s000 - accessdata.fda.gov

Drug interaction study 366-1689 evaluated two-way drug interactions between the components of FTC/RPV/TAF and ledipasvir/sofosbuvir (LDV/SOF).

Juluca (dolutegravir and rilpivirine) tablets

Consider the potential for drug interactions prior to and during therapy with JULUCA; review concomitant medications during therapy with. JULUCA; and monitor ...

Pharmacokinetics and Drug–Drug Interactions of Long-Acting ...

This review provides insight on the intramuscular administration of drugs and summarizes the pharmacology of long-acting cabotegravir and rilpivirine.

Rilpivirine (RPV) - HIV Drug Interactions

No clinically relevant drug-drug interaction is expected when rilpivirine is co-administered with abacavir. Edurant US Prescribing Information, Janssen ...