Evaluation of oral tranexamic acid in the treatment of melasma

We conclude that tranexamic acid was effective in 50% of patients according to four methods of evaluation when compared to the placebo.

Oral Tranexamic Acid for the Treatment of Melasma: A Review

Oral TXA is a safe and efficacious treatment for refractory melasma. It should be considered in cases that are unresponsive to topical hydroquinone and ...

TA has antiplasmin activity and consequently inhibits melanin synthesis by decreasing the level of alpha-melanocyte stimulating hormone (α-MSH).

Evaluation of oral tranexamic acid as a novel treatment for melasma ...

The aim of this paper is to evaluate the safety and baseline efficacy of oral transmexic acid as a treatment for melasma.

Oral Tranexamic Acid for the Treatment of Melasma: A Review

CONCLUSION. Oral TXA is a safe and efficacious treatment for refractory melasma. It should be considered in cases that are unresponsive to topical hydroquinone ...

Oral Tranexamic Acid for the Treatment of Melasma: A Case Series ...

Our case series demonstrates the effectiveness and safety profile of utilizing oral TXA to treat recalcitrant melasma and highlights a possible dosing regimen.

The optimal dose of oral tranexamic acid in melasma

Oral tranexamic acid is a promising drug for melasma. The optimal dose of this drug is 250 mg three times per day for 12 consecutive weeks, but 250 mg twice ...

Oral tranexamic acid treatment beyond 6 months for melasma patients

Oral tranexamic acid (TXA), an antifibrinolytic, is an effective off-label treatment for melasma. However, scarce long-term safety data and ...

Tranexamic acid as a therapeutic option for melasma management

Oral TXA showed the most substantial decrease in MASI scores, followed by injections and topical applications. However, studies exhibited high heterogeneity, ...

Oral Tranexamic Acid for the Treatment of Melasma: A Review

Oral TXA is a safe and efficacious treatment for refractory melasma and should be considered in cases that are unresponsive to topical hydroquinone and ...

Assessing the efficacy of oral tranexamic acid as an adjuvant to ...

Furthermore, the results suggest that the addition of TXA to TCC treatment may reduce melasma recurrence. Issue Section: Review Article.

A closer look at tranexamic acid for melasma - Dermatology Times

In what the authors say is the largest retrospective study of melasma and oral tranexamic acid treatment, 2 researchers studied 561 melasma ...

Tranexamic acid in melasma: Comparative evaluation of therapeutic ...

The use of tranexamic acid (TXA) for the treatment of melasma is a novel concept. It is a plasmin inhibitor and works on melasma by decreasing melanin synthesis ...

Comparison of oral versus topical tranexamic acid for treatment of ...

Background: Melasma is one of the most common causes of hyperpigmentation and is a prevalent cosmetic concern for patients. Tranexemic acid ...

Different administration routes of tranexamic acid in the treatment of ...

Oral administration of TA is the most common for melasma treatment. The efficacy of TA in melasma treatment has been demonstrated in several clinical trials.

Effectiveness of Using Oral Tranexamic Acid as an Adjuvant to ...

This systematic review evaluated the effectiveness and safety of oral tranexamic acid (TXA) as an adjuvant to triple combination cream (TCC) ...

Tranexamic Acid Treatment for Melasma: A Preliminary Analysis

Oral tranexamic acid (TXA), used commonly in East Asia to treat hyperpigmentation during and after pregnancy, was found to be a safe and effective treatment ...

Oral Tranexamic Acid for the Treatment of Melasma - ResearchGate

Conclusions: Oral tranexamic acid is a safe and effective treatment in patients with melasma. Read more. Article. Comparing the Effectiveness of ...

Tranexamic Acid Pill for Melasma - Dr. Michele Green M.D.

However, recent studies of oral tranexamic acid in treating hyperpigmentation and melasma have been quite promising. Clinical trials have confirmed the efficacy ...

Oral tranexamic acid (TA) in the treatment of melasma

Oral tranexamic acid (TA) has emerged as a potential treatment for refractory melasma. Large-scale studies on its use, outcomes, and safety are ...