Evolution of Regulatory Sequences in 12 Drosophila Species

Evolution of Regulatory Sequences in 12 Drosophila Species - PLOS

We find that mutations of nucleotides within a binding site are constrained by evolutionary forces to preserve the site's binding affinity to the cognate ...

Evolution of regulatory sequences in 12 Drosophila species - PubMed

Characterization of the evolutionary constraints acting on cis-regulatory sequences is crucial to comparative genomics and provides key ...

Evolution of Regulatory Sequences in 12 Drosophila Species ...

Figure 1. Correlation between the specificity of a TFBS position and its evolutionary rate in transcription factors Dstat and Kni, with Pecan alignments. More ».

Evolution of regulatory sequences in 12 Drosophila species ...

We study the relationships among orthologous cis-regulatory modules (CRMs) in 12 Drosophila species, especially with respect to the evolution of transcription ...

[PDF] Evolution of Regulatory Sequences in 12 Drosophila Species

The relationships among orthologous cis-regulatory modules (CRMs) in 12 Drosophila species are studied, especially with respect to the evolution of ...

Evolution of Regulatory Sequences in 12 Drosophila Species - OUCI

EH Davidson, The Regulatory Genome: Gene Regulatory Networks in Development and Evolution; PJ Wittkopp, Variable gene expression in eukaryotes: a network ...

Tracing the Evolutionary History of Drosophila Regulatory Regions ...

In light of recent data indicating that transcription factor binding sites undergo substantial turnover between species, we attempt to quantify the process of ...

Identification of Motifs That Are Conserved in 12 Drosophila Species ...

These results suggest short, highly conserved genomic sequences flanking Drosophila midline genes are indicative of functional regulatory regions and that small ...

A cis-regulatory sequence of the selector gene vestigial drives the ...

A cis-regulatory sequence of the selector gene vestigial drives the evolution of wing scaling in Drosophila species Icon for The Forest of ...

Evolution of cis-regulatory sequence and function in Diptera | Heredity

Comparative studies of gene regulation among Diptera reveal that divergent sequences can underlie conserved expression, and that expression differences can ...

Evolutionary Analysis of Amino Acid Repeats across the Genomes ...

Using the set of 1-to-1 ortholog alignments for the 12 Drosophila species, we test the ability of repeats to act as reliable phylogenetic signals and find that ...

Emerging principles of regulatory evolution - PNAS

In the Drosophila haltere, Ubx directly represses the expression of a set of wing-patterning genes (64, 65). In contrast, in four-winged ...

Evolution of protein-coding genes in Drosophila - ScienceDirect.com

The recently sequenced 12 Drosophila genomes provide a unique opportunity to shed light on these unresolved issues. Here, we focus on the role of natural ...

A cis-regulatory sequence of the selector gene vestigial drives the ...

the evolution of wing scaling in Drosophila species. Keity J. Farfán-Pira1 ... (B) Alignment of representative and conserved regions of vgQE sequences in ...

In silico evolution of the Drosophila gap gene regulatory sequence ...

We observe a dramatic decrease in the total number of transcription factor binding sites through the course of evolution. Despite a decrease in ...

Evolutionary origin of a novel gene expression pattern through co ...

Here, we sought to explore the molecular genetic mechanisms by which new enhancers arise. We undertook a survey of closely related Drosophila species to ...

The Evolution of Gene Regulation Underlies a Morphological ...

We analyze the genetic and molecular bases of the divergence of body pigmentation patterns between Drosophila yakuba and its sister species Drosophila santomea.

Chapter 3 Evolution of Cis‐Regulatory Sequences in Drosophila

Alonso, The achaete‐scute gene complex of Drosophila melanogaster comprises four homologous genes, EMBO J., № 7, с. · Arnone, The hardwiring of development: ...

The evolution of hierarchical gene regulatory networks - Carol Lee

The binding of transcription factors to regulatory DNA sequences controls the spatial and temporal expression of genes in the developing ...

Research proposal: Evolution of the Dorsal-Ventral gene regulatory ...

Research proposal: Evolution of the Dorsal-Ventral gene regulatory network in Drosophila species ... Gene regulation in animals is arguably at ...