Evolving models for assembling and shaping clathrin|coated pits

Evolving models for assembling and shaping clathrin-coated pits

Clathrin-mediated endocytosis occurs via the assembly of clathrin-coated pits (CCPs) that invaginate and pinch off to form clathrin-coated ...

Evolving models for assembling and shaping clathrin-coated pits

Clathrin-mediated endocytosis occurs via the assembly of clathrin-coated pits (CCPs) that invaginate and pinch off to form clathrin-coated vesicles (CCVs).

Evolving models for assembling and shaping clathrin-coated pits

Integrating recent findings, Chen and Schmid present a more dynamic, flexible, and nonlinear model for clathrin-coated vesicle formation.

Evolving models for assembling and shaping clathrin-coated pits

Numerous endocytic accessory proteins collaborate with clathrin and AP2 to drive CCV formation. However, many questions remain as to the ...

Evolving models for assembling and shaping clathrin-coated pits

Evolving models for assembling and shaping clathrin-coated pits · Journal of Cell Biology, August 2020 · 10.1083/jcb.202005126 · 32770195 · Zhiming Chen, Sandra L.

JCellBiol on X: "Evolving models for assembling and shaping ...

Evolving models for assembling and shaping clathrin-coated pits. Zhiming Chen and Sandra L. Schmid @slschmid_lab present a more dynamic, ...

Clathrin coats partially preassemble and subsequently bend during ...

We find that clathrin coats assemble first on flat membranes to 50% of the coat area before they become rapidly and continuously bent.

Capturing the mechanics of clathrin-mediated endocytosis

The defining events in clathrin-coated vesicle formation; selection of receptors, membrane bending, progression from coated pit to fully formed vesicle and ...

De novo endocytic clathrin coats develop curvature at early stages ...

Detailed analyses of the footprint and the fluorescence intensity of assembling clathrin pits have revealed that these structures do not undergo ...

CCDC32 stabilizes clathrin-coated pits and drives their invagination

Chen, S. L. Schmid, Evolving models for assembling and shaping clathrin-coated pits. Journal of Cell Biology 219 (2020). Google Scholar. 17 ...

Recruitment of clathrin to intracellular membranes is sufficient ... - eLife

Endogenous clathrin assembled to form coated pits on the mitochondria, termed MitoPits, within seconds of induction. MitoPits are double- ...

Imaging vesicle formation dynamics supports the flexible model of ...

Clathrin, a building block of clathrin-coated vesicles (CCVs), is a trimeric coat protein composed of three heavy and three light chains. This ...

Clathrin assemblies at a glance - Company of Biologists Journals

Because of their shape and composition, these membrane invaginations are termed clathrin-coated pits (CCPs). Decades of research have ...

Membrane shaping for clathrin-coated pits and endocytosis - OUCI

Chen, Evolving models for assembling and shaping clathrin-coated pits, Journal of Cell Biology, № 219, с. e202005126 https://doi.org/10.1083/jcb.202005126 ...

Clathrin: the molecular shape shifter | Biochemical Journal

Clathrin assembles into empty coat structures in vitro, also known as clathrin cages or baskets, if placed in a buffer at pH 6.5 or less with magnesium and ...

Review From Flat to Curved Clathrin: Controlling a Plastic Ratchet

Evolving models for assembling and shaping clathrin-coated pits. 2020, Journal of Cell Biology. The cell biology of mitochondrial membrane dynamics. 2020 ...

Superresolution microscopy reveals partial preassembly and ...

We find that clathrin coats assemble first on flat membranes to 50% of the coat area, before they become rapidly and continuously bent, and ...

Evolutionarily unique mechanistic framework of clathrin-mediated ...

Clathrin mediated endocytosis (CME) is the key cellular progress of internalising a cargo, either on the plasma membrane (PM) or outside the ...

Capturing the mechanics of clathrin-mediated endocytosis

Schematic diagram illustrating the assembly and disassembly of a clathrin-coated pit. ... Chen Z, Schmid SL: Evolving models for assembling and · shaping clathrin ...

De novo endocytic clathrin coats develop curvature at early stages ...

Evolving models for assembling and · shaping clathrin-coated pits. J. Cell Biol. 219, e202005126. Cheng, Y., Boll, W., Kirchhausen, T ...