Expected and unexpected effects after systemic inhibition of Hippo ...

Hyperactivation of YAP/TAZ, the Hippo pathway downstream effectors, is common in human cancer. The requirement of YAP/TAZ for cancer cell ...

The tumourigenic potential of this pathway is largely attributed to the activity of YAP/TAZ, which activate the TEAD1‐4 transcription factors, leading to the ...

Expected and unexpected effects after systemic inhibition of Hippo ...

AbstractHyperactivation of YAP/TAZ, the Hippo pathway downstream effectors, is common in human cancer. The requirement of YAP/TAZ for cancer cell survival ...

Expected and unexpected effects after systemic inhibition of Hippo ...

About this Attention Score · In the top 25% of all research outputs scored by Altmetric · High Attention Score compared to outputs of the same age (85th ...

Review Therapeutic targeting of TEAD transcription factors in cancer

Cited by (41) · Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer · Direct and selective pharmacological ...

The two faces of Hippo: targeting the Hippo pathway for ...

Defects in Hippo signaling and hyperactivation of its downstream effectors YAP and TAZ contribute to the development of cancer, suggesting that ...

‪Iván M. Moya‬ - ‪Google Scholar‬

Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer. I Baroja, NC Kyriakidis, G Halder, IM Moya. Nature ...

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Hippo signaling dysfunction induces cancer cell addiction to YAP ...

Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer ... Inactivation of YAP oncoprotein by the Hippo pathway is ...

Reviews & Analysis | Nature Communications

Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer · Isabel Baroja · Nikolaos C. Kyriakidis · Iván M. Moya.

Hippo Pathway Gene Mutations in Malignant Mesothelioma ...

Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer · Isabel BarojaNicolaos C KyriakidisGeorg HalderI. Moya.

Georg Halder (0000-0001-7580-3236) - ORCID

Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer. Nature Communications. 2024-03-27 | Journal article. DOI ...

[PDF] Hippo signaling pathway regulates cancer cell-intrinsic MHC-II ...

bioRxiv. 2023. TLDR. It is reported that inhibition of the Hippo ... Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in ...

The regulation of Yorkie, YAP and TAZ: New insights into the Hippo ...

Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer. Article. Full-text available. Mar 2024. Isabel Baroja ...

Hippo effector, Yorkie, is a tumor suppressor in select Drosophila ...

Moya, Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer. Nat. Commun. 15, 2700 (2024). 35 ...

A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo ...

... inhibitor that has potential to treat multiple Hippo ... Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer.

Natural compounds targeting YAP/TAZ axis in cancer: Current state ...

This pathway is a kinase cascade that starts from the tumor suppressor Hippo (MST1 and MST2 in mammals) and culminates with the oncoprotein Yorkie (Yki; YAP in ...

Insights into recent findings and clinical application of YAP and TAZ ...

Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer. · Catastrophic conformity. · The mTORC2 signaling network: ...

The Hippo transducer TAZ confers cancer stem cell-related traits on ...

Article citations · Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer. · YAP/TAZ-TEAD activity promotes the ...

Citations to YAP/TAZ regulates sprouting angiogenesis and ... - JCI

Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer. Baroja I, Kyriakidis NC, Halder G, Moya IM, Nature ...