Exploring clinical markers of Axon degeneration processes in ...

This is the first study to measure plasma NAD + , cADPR, and ADPR among patients receiving neurotoxic chemotherapy.

Approximately 70% of patients receiving neurotoxic chemotherapy (e.g., paclitaxel or vincristine) will develop chemotherapy-induced peripheral neuropathy.

(PDF) Exploring clinical markers of Axon degeneration processes in ...

Nicotinamide adenine dinucleotide (NAD⁺) and cyclic-adenosine diphosphate ribose (cADPR) are potential markers of axon degeneration following ...

Exploring clinical markers of Axon degeneration processes in ...

Exploring clinical markers of Axon degeneration processes in Chemotherapy-induced peripheral neuropathy among young adults receiving vincristine or paclitaxel.

Exploring clinical markers of Axon degeneration processes in ...

The symptoms of chemotherapy-induced peripheral neuropathy (CIPN) following neurotoxic chemotherapy administration (e.g., vincristine or paclitaxel)

Additional file 1 of Exploring clinical markers of Axon degeneration ...

Additional file 1 of Exploring clinical markers of Axon degeneration processes in Chemotherapy-induced peripheral neuropathy among young adults receiving ...

Exploring clinical markers of Axon degeneration processes in ...

Abstract Background Approximately 70% of patients receiving neurotoxic chemotherapy (e.g., paclitaxel or vincristine) will develop chemotherapy-induced ...

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... Exploring clinical markers of Axon degeneration processes in Chemotherapy-induced peripheral neuropathy among young adults receiving vincristine or ...

Axonal degeneration in chemotherapy-induced peripheral ...

We will highlight potential clinical markers of axonal dysfunction to provide early identification of toxicity as well as present potential treatment strategies ...

Axonal degeneration in chemotherapy-induced peripheral ... - X-MOL

Exploring clinical markers of Axon degeneration processes in Chemotherapy-induced peripheral neuropathy among young adults receiving ...

A Mechanistic Understanding of Axon Degeneration in ...

Exploring clinical markers of Axon degeneration processes in Chemotherapy-induced peripheral neuropathy among young adults receiving vincristine or paclitaxel.

induced peripheral neurotoxicity: clinical and experimental evidence

We review likely triggers of axonal degeneration in CIPN and highlight evidence of molecular pathways involved in axonal degeneration and their ...

A Mechanistic Understanding of Axon Degeneration in ... - Frontiers

Although sensory neurons represent the most common target of CIPN, damage to motor and autonomic neurons have also been reported (Mora et al., 2016). Behavioral ...

Clinical Progression in Parkinson's Disease and the Neurobiology of ...

We propose that it is ongoing degeneration of axons, not cell bodies, that is the primary determinant of clinically apparent progression of disease, and that ...

Citations to Vincristine and bortezomib use distinct ... - JCI Insight

Citations to this article in year 2024 (17) ; Exploring clinical markers of Axon degeneration processes in Chemotherapy-induced peripheral neuropathy among young ...

Axonal Degeneration - an overview | ScienceDirect Topics

Axonal degeneration is a prominent pathological feature in many neurological diseases (Lingor et al., 2012). In neurodegenerative diseases like Parkinson's ...

Axonal Degeneration during Aging and Its Functional Role in ...

Importantly, the degeneration of axons represents an early event during the development of NDs, preceding both cell death and the onset of clinical symptoms, ...

Evidence for dopaminergic axonal degeneration as an early ...

Highlights · Profound dopaminergic axonal loss occurs at early stages of Parkinson's disease. · iPSC-derived dopaminergic neurons from patients show signs of ...

Myelin insulation as a risk factor for axonal degeneration in ... - Nature

Axonal degeneration determines the clinical outcome of multiple sclerosis and ... axon continuity (without signs of axonal constrictions) ...

Programmed axon degeneration: from mouse to mechanism to ...

Severed axons almost completely disintegrate in two days by Wallerian degeneration, and this process is completely prevented by expressing Wlds, a gain-of- ...