Exploring the Target Genes of Fucosylated Chondroitin Sulfate in ...

Exploring the Target Genes of Fucosylated Chondroitin Sulfate in Treating Lung Adenocarcinoma Based on the Integration of Bioinformatics ...

Fucosylated chondroitin sulfate (FCS), extracted from sea cucumbers' body walls, has been found to inhibit the proliferation of lung adenocarcinoma (LUAD) ...

Holothurian Fucosylated Chondroitin Sulfate - PMC - PubMed Central

Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of ...

Exploring the Mechanism of Chondroitin Sulfate-Selenium ...

Therefore, CS holds potential as a multi-target drug for the treatment of AD. Selenium, an essential trace element in the human body, plays a ...

Exploring the structure of fucosylated chondroitin sulfate through ...

CS cores and sulfated fucose branches, obtained via systematic fragmentation through mild acid hydrolysis. Oligosaccharides derived from the ...

Chemical Synthesis of Fucosylated Chondroitin Sulfate ... - MDPI

Fucosylated chondroitin sulfate is a unique glycosaminoglycan isolated from sea cucumbers, with excellent anticoagulant activity. The fucosyl branch in FCS ...

Complete biosynthesis of a sulfated chondroitin in Escherichia coli

coli to produce all three required components for CS production–chondroitin, sulfate donor and sulfotransferase. In this way, we achieve ...

Fucosylated chondroitin sulphate from sea cucumber reduces ...

Fucosylated chondroitin sulphate from Acaudina molpadioides (Am-CHS) can mitigate insulin resistance. However, its effects on ER stress and inflammation are ...

Fucosylated Chondroitin Sulfate from Bohadschia ocellata: Structure ...

Fucosylated chondroitin sulfate (FCS) was prepared from Bohadschia ocellata using protease hydrolysis. The structural characteristics of FCS were confirmed ...

Chondroitin: a natural biomarker with immense biomedical ...

A structurally distinct glycosaminoglycan, fucosylated chondroitin sulfate (FCS), was isolated from the body wall of sea cucumber; it possesses ...

Comparative Proteomic Analysis of Fucosylated Glycoproteins ...

Q8A818 is a capsular polysaccharide transport protein that can transport polysaccharides to the capsule of B. thetaiotaomicron, resulting in the formation of ...

The Fin‐Improving Effects of Fucosylated Chondroitin Sulfate from ...

Moreover, FCS promoted the mRNA expression of inflammatory factors (iNOS, TNF-α, IL-6, IL-10, and IFN-γ) and TLR/NF-κB pathway-related genes ( ...

Fucosylated chondroitin sulfate from sea cucumber inhibited islets of ...

Fucosylated chondroitin sulfate from sea cucumber inhibited islets of langerhans apoptosis via inactivation of the mitochondrial pathway in insulin resistant ...

Expanding the Chondroitin Sulfate Glycoproteome — But How Far?

Moreover, an unexpected fucose (deoxy-hexose) modification was found on the xylose residue of the linkage region of human bikunin and decorin ...

Medical Gains of Chondroitin Sulfate Upon Fucosylation

CS is a key functional component in proteoglycans of cartilaginous tissues. Owing to its numerous biological roles, CS is widely explored in the pharmaceutical ...

Fucosylated chondroitin sulfate from Acaudina molpadioides ...

Fucosylated chondroitin sulfate from Acaudina molpadioides improves hyperglycemia via activation of PKB/GLUT4 signaling in skeletal muscle of insulin resistant ...

Chondroitin sulfated,chondroitin sulfate - Sigma-Aldrich

Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development. Beata Filipek-Górniok et al.

Identification of novel anti-obesity saponins from the ovary of sea ...

], whereas fucosylated chondroitin sulfates have been shown to ... gene to calibrate the expression levels of the target genes. 2.12 ...

Glycogenes in Oncofetal Chondroitin Sulfate Biosynthesis ... - Frontiers

Here, by examining the glycogenes availability in chondroitin sulfate biosynthesis such as xylosytransferase, chondroitin synthase, sulfotransferase, and ...

Chondroitin sulfate expression predicts poor outcome in breast cancer

Studies aimed at the identification of prognostic biomarkers and treatment targets of cancer have, so far, focused on proteins typically expressed by malignant ...