Expression and activation of the nerve growth factor receptor TrkA in ...

Coexpression of NGF with molecules involved in angiogenesis and p-TrkA expression in endothelial cells suggest that the proangiogenic role attributed to NGF ...

Expression and Activation of the Nerve Growth Factor Receptor TrkA ...

In conclusion, the expression and activation of the neurotrophin receptor TrkA is reduced in effusions compared with solid ovarian carcinoma and appears to be ...

Expression and Activation of the Nerve Growth Factor Receptor TrkA ...

Expression and Activation of the Nerve Growth Factor Receptor. TrkA in Serous Ovarian Carcinoma. Ben Davidson,1 Reuven Reich,2 Philip Lazarovici,2. Jahn M ...

Activation of TrkA by nerve growth factor upregulates expression of ...

Activation of TrkA by nerve growth factor upregulates expression of the cholinergic gene locus but attenuates the response to ciliary neurotrophic growth factor ...

Ligand activation of nerve growth factor receptor TrkA protects ...

TrkA stimulation up-regulates the expression of the anti-apoptotic Bcl-2 family members, Bcl-2, Bcl-XL, and Bfl-1. On the other hand, TrkA ...

Activation of TrkA by nerve growth factor upregulates expression of ...

Activation of TrkA by nerve growth factor upregulates expression of the cholinergic gene locus but attenuates the response to ciliary neurotrophic growth factor.

Expression and Functionality of the trkA Proto-Oncogene Product ...

The expression of the low-affinity NGF receptor (p75) and the trkA proto-oncogene product was analyzed in a series of human hematopoietic cell lines at ...

Altered Expression and Activation of the Nerve Growth Factor ...

Altered Expression and Activation of the Nerve Growth Factor Receptors TrkA and p75 Provide the First Evidence of Tumor Progression to Effusion in Breast ...

Nerve growth factor & TrkA as novel therapeutic targets in cancer

In the past 20 years, nerve growth factor (NGF) and its receptors TrkA & p75NTR were recognized to be overexpressed in the overwhelming majority of human ...

mKlf7, a potential transcriptional regulator of TrkA nerve growth ...

Development of the nervous system relies on stringent regulation of genes that are crucial to this process. TrkA, the receptor for nerve ...

Ligand activation of nerve growth factor receptor TrkA protects ...

In addition, during in vitro monocyte to dendritic cell differentiation TrkA expression is progres- sively lost, suggesting that NGF selectively affects.

TrkA cross-linking mimics neuronal responses to nerve growth factor.

The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signaling pathways, resulting in diverse ...

Antagonism of Nerve Growth Factor-TrkA Signaling and the Relief of ...

A role for NGF has been demonstrated in acute, transient nociceptive responses and in longer-term, chronic pain.42–45As early as 1977, a report that NGF exerts ...

Increased expression of nerve growth factor (NGF) and high affinity ...

Conclusions. This is the first study showing that human chondrocytes synthesize NFG‐β and express on their surface the high affinity NGFR (p140 TrkA). Of note, ...

Significance of nerve growth factor overexpression and its autocrine ...

NGF overexpression was also associated with strong expression of TrkA and negative expression of low-affinity neurotrophin receptor (p75NTR).

Expression of Nerve Growth Factor (NGF), TrkA, and p75 ... - Frontiers

NGF binds to specific low- and high-affinity cell surface receptors, respectively, p75NTR and TrkA. In the present study, we examined by ...

Expression of the Nerve Growth Factor Receptors TrkA and p75NTR ...

p75NTR can modify the binding and function of neurotrophins when coexpressed with Trks. In the absence of Trks, NGF activation of p75NTR may induce a cell death ...

Spatio-temporal expression profile of NGF and the two-receptor ...

Nerve growth factor (NGF) and its receptors, tropomyosin receptor kinase A (TrkA) and pan-neurotrophin receptor p75 (p75NTR), ...

"Nerve Growth Factor Activation of the TrkA Receptor Induces Cell ...

Ectopic expression of the TrkA receptor tyrosine kinase in tumors of the nervous system can mediate nerve growth factor (NGF)-dependent cell death by ...

Brn3a regulation of TrkA/NGF receptor expression in developing ...

The TrkA/NGF receptor is essential for the survival and differentiation of sensory neurons. The molecular mechanisms regulating tissue and ...