Expression and clinical significance of the m6A reader YTHDF2 in ...

As an important m6A reader, the YT521-B homology domain family 2 (YTHDF2) has been shown to regulate mRNA degradation and translation, and to be involved in ...

The present study illustrated that YTHDF2 expression might have some regulatory role in the underlying mechanisms associated with the autoimmune disease RA.

Expression and Clinical Significance of the m6A RNA-Binding ...

The data showed that the mRNA expressions of YTHDF2 and ALKBH5 in PBMC from patients with new-onset AS were significantly decreased, and there ...

Expression and Clinical Significance of the m6A RNA-Binding ...

This study indicates that the mRNA expression of YTHDF2 in PBMC may be involved in AS pathogenesis and a predictive model based on a combination of mRNA YTHDF2 ...

Expression and clinical significance of the m6A reader YTHDF2 in ...

Expression and clinical significance of the m6A reader YTHDF2 in peripheral blood mononuclear cells from rheumatoid arthritis patients.

The RNA m6A Reader YTHDF2 Maintains Oncogene Expression ...

RNA m6A landscapes of cancer and NSCs identified cell type–specific dependencies and therapeutic vulnerabilities. The m6A reader YTHDF2 stabilized MYC mRNA ...

(PDF) Expression and Clinical Significance of the m6A RNA-Binding ...

This study indicates that the mRNA expression of YTHDF2 in PBMC may be involved in AS pathogenesis and a predictive model based on a combination of mRNA YTHDF2 ...

The biological function of m6A reader YTHDF2 and its role in human ...

N6-methyladenosine (m6A) modification is a dynamic and reversible post-transcriptional modification and the most prevalent internal RNA ...

Comprehensive analysis of m6A reader YTHDF2 prognosis ...

However, the expression of m6A regulator YTHDF2, its prognostic value, its biological function, its correlation with tumor microenvironment ...

The RNA m6A Reader YTHDF2 Maintains Oncogene Expression ...

SIGNIFICANCE: Epitranscriptomics promotes cellular heterogeneity in cancer. RNA m6A landscapes of cancer and NSCs identified cell type ...

The RNA m6A reader YTHDF2 controls NK cell antitumor and ...

NK cells are critical mediators of host immunity against viral infection and malignancies (Spits et al., 2016). We therefore evaluated the expression pattern of ...

Bioinformatic analysis of m6A “reader” YTH family in pan-cancer as ...

The expression of RNA methylation YTH domain family member was calculated and evaluated (Fig. 1A,B). YTHDF1 was elevated in 14 of the 17 tumors ...

The tumor-intrinsic role of the m6A reader YTHDF2 in regulating ...

Inhibiting DNA methylation induces type I interferon (IFN) expression and tumor regression (11). These studies indicate that tumor cells evade ...

YTHDF2 is a Potential Biomarker and Associated with Immune ...

Among the m6A reader proteins, YTHDF2 was the first to be recognized and studied extensively, affecting mRNA stability (Chandrashekar et al., ...

YTHDF2 inhibition potentiates radiotherapy antitumor efficacy

IR-induced YTHDF2 expression relies on NF-κB signaling; YTHDF2 in turn leads to NF-κB activation by directly binding and degrading transcripts ...

m6A binding protein YTHDF2 in cancer

Furthermore, YTHDF2 is closely associated with the proliferation, apoptosis, invasion, and migration of tumor cells, suggesting its significant ...

RNA m6A reader YTHDF2 facilitates lung adenocarcinoma cell ...

In our present study, we showed that YTHDF2 expression was abnormally up-regulated in LUAD, and that YTHDF2 was crucial for lung cancer cell ...

Clinical implications of m6A‐related regulators YTHDF1 and ...

Bioinformatics examination revealed that YTHDF1 and YTHDF2 expression was increased in HCC tissues, and poor pathology grade and prognosis were ...

The RNA m6A Reader YTHDF2 Is Essential for the Post ...

YTHDF2 binds and destabilizes N6-methyladenosine (m6A)-modified mRNA. The extent to which this branch of m6A RNA-regulatory pathway functions in ...

The mRNA m 6 A reader YTHDF2 suppresses proinflammatory ...

The m6A reader YTHDF2 is a novel regulator of inflammatory pathways in HSCs. YTHDF2 loss upregulates m6A-modified proinflammatory ...