Expression of CXCR4 Predicts Poor Prognosis in Patients with ...

Expression of CXCR4 predicts poor prognosis in patients ... - PubMed

This article provides the first evidence that CXCR4 expression could be an independent and powerful prognostic marker in primary cutaneous malignant melanomas.

After a median follow-up of 38 months, 26 patients progressed (16 of 26 expressed CXCR4) and 19 died (12 of 19 expressed CXCR4). The CXCR4 expression on tumor ...

Expression of CXCR4 Predicts Poor Prognosis in Patients with ...

Expression of CXCR4 Predicts Poor Prognosis in Patients with Malignant Melanoma. Stefania Scala,1 Alessandro Ottaiano,1. Paolo Antonio Ascierto,1 Manuela ...

CXCR4 over-expression and survival in cancer: A system review ...

In conclusion, CXCR4 over-expression is associated with poor prognosis in cancer. Keywords: CXCR4, cancer, survival, prognostic biomarker, meta-analysis ...

High CXCR4 Expression Predicts a Poor Prognosis in Resected ...

Clinically, high CXCR4 expression was significantly associated with solid ASC, lymph node metastasis and advanced TNM stage. Patients with high CXCR4 expression ...

(PDF) Expression of CXCR4 Predicts Poor Prognosis in Patients ...

ArticlePDF Available. Expression of CXCR4 Predicts Poor Prognosis in Patients with Malignant Melanoma. March 2005; Clinical Cancer Research 11(5):1835-41. 11(5): ...

High expression of CXCR4 may predict poor survival in resected ...

Patients with CXCR4 high tumour expression had shorter OS than those with low expression (median survival: 9.7 vs 43.2 months, P=0.0006), a higher risk of LN ...

The clinicopathological and prognostic value of CXCR4 expression ...

As shown in Table 2, the stratified analysis by histology demonstrated that high expression of CXCR4 predicted unfavorable OS in both NSCLC (HR ...

Chemokine receptor CXCR4 expression and prognosis in patients ...

For example, there are a few studies reporting that CXCR4 expression predicts poor prognosis in lung cancer,() melanoma,() esophageal cancer,() ...

Overexpression of chemokine receptor CXCR4 predicts lymph node ...

This meta-analysis was performed to explore whether the CXCR4 expression affects prognosis and clinicopathologic features in melanoma cancer. Our study involved ...

High expression of CXCR4, CXCR7 and SDF-1 predicts poor ...

High levels of CXCR4, CXCR7 and SDF-1 were associated with poor overall survival and recurrence-free survival in renal cell carcinoma patients.

Coexpression of EGFR and CXCR4 Predicts Poor Prognosis ... - PLOS

By univariate survival analysis, both CXCR4 expression and EGFR/CXCR4 coexpression were significant prognostic factors for poor disease-free survival (DFS) and ...

Prognostic Value of High CXCR4 Expression in Renal Cell ...

Conclusion. The results of meta-analysis indicated that high CXCR4 expression was correlated with worse OS and PFS for patients with RCC.

High Expression of CXCR4 and CXCR7 Predicts Poor Survival in ...

Expression of either CXCR7 or CXCR4 in the cytoplasm was associated with tumour stage. Expression of nuclear CXCR4 was associated with lymph node metastases and ...

The impact of chemokine receptor CXCR4 on breast cancer prognosis

Conclusions: Increased CXCR4 expression, especially in whole cells and cytoplasm, may serve as a poor prognostic indicator in patients with breast cancer.

High Cytoplasmic CXCR4 Expression Predicts Prolonged Survival ...

A number of studies have reported that increased CXCR4 expression is associated with worse prognosis in triple-negative breast cancer (TNBC), ...

Can Expression of CXCL12 and CXCR4 Be Used to Predict Survival ...

Conclusion: CXCL12 was not associated with survival. Positive CXCR4 expression in gastric carcinoma was significantly associated with poor survival and, ...

EGFR expression is associated with cytoplasmic staining of CXCR4 ...

A strong correlation between CXCR4 and EGFR expression was identified in patients with TNBC. The results suggest that elevated expression levels ...

Concomitant CXCR4 and CXCR7 Expression Predicts Poor ...

CXCR4 expression was low in 42/223 RCC (18,8%), intermediate in 71/223 (31,9%) and high in 110/223 (49,3%). CXCR7 expression was low in 44/223 RCC patients (19, ...

Can Expression of CXCL12 and CXCR4 Be Used to Predict Survival ...

However, patients with advanced gastric cancer have a poor prognosis and although various treatments have been developed, currently there is no effective ...