FIRRM cooperates with FIGNL1 to promote RAD51 disassembly ...

We showed that FIRRM, like its interactor Fidgetin like 1 (FIGNL1), contributes to the resolution of RAD51 foci at ICL-induced DSBs.

We showed that FIRRM, like its interactor Fidgetin like 1 (FIGNL1), contributes to the resolution of RAD51 foci at ICL-induced DSBs.

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly ...

Interstrand DNA cross-links (ICLs) represent complex lesions that compromise genomic stability. Several pathways have been involved in ICL repair, ...

FIGNL1-FIRRM is essential for meiotic recombination and prevents ...

During meiosis, nucleoprotein filaments of the strand exchange proteins RAD51 and DMC1 are crucial for repairing SPO11-generated DNA ...

FIRRM and FIGNL1: partners in the regulation of homologous ...

DNA repair through homologous recombination (HR) is of vital importance for maintaining genome stability and preventing tumorigenesis. RAD51 ...

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly ...

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair · About this Attention Score · Mentioned by · Citations · Readers on.

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FIRRM and FIGNL1: partners in the regulation of homologous ...

(C) FIRRM interacts with FIGNL1 to promote the disassembly of RAD51 from chromatin during homologous recombination once strand invasion and homology search are ...

FIRRM and FIGNL1: partners in the regulation of homologous ...

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair · E. Pinedo-CarpioJulien Dessapt +16 authors. Alexandre Orthwein. Biology, Medicine.

Molecular basis of FIGNL1 in dissociating RAD51 from DNA and ...

Mutations in pore loop or catalytic residues of FIGNL1 render it defective in filament disassembly and are lethal in mouse embryonic stem cells.

Molecular basis of FIGNL1 in dissociating RAD51 from DNA and ...

Pinedo-Carpio et al., FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair. Sci. Adv. 9, eadf4082 (2023). 25. J. D. ...

FIGNL1 dismantles RAD51 from ssDNA. a Schematics of RAD51 ...

... FIGL1 is also recruited to sites of DNA repair independently of RAD51 (Yuan & Chen, 2013), and promotes the subsequent dissociation of RAD51 and DMC1 ( ...

FIGNL1-FIRRM is essential for meiotic recombination and prevents ...

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair · E. Pinedo-CarpioJulien Dessapt +16 authors. Alexandre Orthwein. Biology, Medicine.

Winship Cancer Institute of Emory University on X: "RT ...

and @DessaptJcharacterized the critical role of FIRRM/C1orf112 in the disassembly of RAD51 during DNA repair. ... science.orgFIRRM cooperates with ...

FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre ...

Fignl1 cKO male mice showed defective chromosome synapsis and impaired meiotic DSB repair with the accumulation of RAD51/DMC1 on meiotic ...

The FIGNL1-FIRRM complex is required to complete meiotic ... - OUCI

AbstractDuring meiosis, nucleoprotein filaments of the strand exchange proteins RAD51 and DMC1 are crucial for repairing SPO11-generated DNA double-strand ...

FIGNL1-containing protein complex is required for efficient ...

The RAD51 recombinase plays a central role in homologous recombination (HR), which is critical for repair of DNA double-strand breaks, maintenance of ...

FIGNL1-FIRRM is essential for meiotic recombination and prevents ...

FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA damage-independent RAD51 and DMC1 loading ... Authors: Akbar Zainu; Pauline Dupaigne; Soumya ...

‪Julien Dessapt‬ - ‪Google Scholar‬

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair. E Pinedo-Carpio, J Dessapt, A Beneyton, L Sacre, MA Bérubé, R Villot ...

HELQ - DISEASES

FLIP(C1orf112)-FIGNL1 complex regulates RAD51 chromatin association to promote ... FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair.