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Fetus specific T cell modulation during fertilization


Fetus specific T cell modulation during fertilization, implantation and ...

Especially the induction, already before conception, of feto-specific T cells with a possibly regulatory function gives a biological explanation ...

Fetus specific T cell modulation during fertilization, implantation and ...

This review highlights besides uNK cells, especially the function of CD4 + and CD8 + T cells with a regulatory function in the context of recurrent miscarriage ...

Maternal and fetal T cells in term pregnancy and preterm labor - PMC

... T cell-specific transcriptional signatures derived from the maternal–fetal interface are modulated during pregnancy, in term labor, and in preterm labor.

(PDF) Fetus specific T cell modulation during fertilization ...

PDF | Recently there is an increasing interest in aspects of a more specific immunoregulation during pregnancy. Understanding these mechanism might have.

Mechanisms of Fetal T Cell Tolerance and Immune Regulation

Fetal immune tolerance is essential to the maintenance of pregnancy, achieved in large part by the ability of Treg cells to suppress the ...

The New Old CD8+ T Cells in the Immune Paradox of Pregnancy

Of particular abundance in the early pregnant uterus, NK cells are critical for vascular changes and trophoblast invasion in early pregnancy (4) ...

Fetal-Specific CD8+ Cytotoxic T Cell Responses Develop during ...

These data show that the development of a fetal-specific adaptive cellular immune response is a normal consequence of human pregnancy and that unlike reports ...

Regulatory T cells in embryo implantation and the immune ... - JCI

To ensure a robust placenta and sustainable pregnancy, an active state of maternal immune tolerance mediated by CD4+ regulatory T cells (Tregs) ...

Fetus specific T cell modulation during fertilization, implantation and ...

List of references · Sutton, HLA-DR positive cells in the placenta, Immunology, № 49, с. 103 · Williams, Foreign fetal cells persist in the maternal circulation, ...

Immunologic Regulation in Pregnancy: From Mechanism to ...

In human hemochorial placenta, fetal trophoblast cells appear to be in extremely close contact with the maternal immune cells, based on the ...

Fetal Antigen - an overview | ScienceDirect Topics

Antigen-specific T cells of the fetus cause feto-maternal immune tolerance during pregnancy, such as T cell tolerance [3,4]. The in vivo operational tolerance ...

Regulatory T-cells and immune tolerance in pregnancy: a new target ...

Adaptation of the maternal immune response to accommodate the semi-allogeneic fetus is necessary for pregnancy success, and disturbances in maternal ...

Profile of maternal CD4 T-cell effector function during normal ...

The traditional paradigm suggests that during normal pregnancy maternal immunological tolerance of the allogenic fetus is association with a maternal ...

The maternal immune system during pregnancy and its influence on ...

With regard to decidual immune cell populations during early pregnancy, studies using flow cytometry and immunostaining of human tissues ...

Modulation of galectin-9 mediated responses in monocytes and T ...

Among the molecules supporting placental development and maternal tolerance, the families of pregnancy-specific glycoproteins and galectins are of great ...

Three Types of Functional Regulatory T Cells Control T Cell ...

During pregnancy, maternal regulatory T cells (Tregs) are important in establishing immune tolerance to invading fetal extravillous ...

Changes in peripheral immune populations during pregnancy and ...

In an effort to map the peripheral immunity during pregnancy we stained cells for these specific transcription factors, finding that the ...

The influence of pregnancy on systemic immunity - SpringerLink

We have found a decrease in the total number of CD3+ T cells in blood. The surge in estrogen and progesterone at the end of the first trimester ...

Cytokines and pregnancy complications: modulation for prevention ...

Maternal immune reactions that can adversely affect pregnancy have been shown to be mediated by lymphocytes, macrophages and natural killer ...

Cancer and Pregnancy: Parallels in Growth, Invasion, and Immune ...

In addition to the shared capacity for invading through normal tissues, both cancer cells and cells of the developing placenta create a microenvironment ...