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- Cardiac anaplerosis in health and disease🔍
- Investigation of anaplerosis from propionyl|CoA precursors and fatty ...🔍
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- Ins and Outs of the TCA Cycle🔍
Figure 1 from Assessing the Reversibility of the Anaplerotic ...
Assessing the Reversibility of the Anaplerotic Reactions of the ...
In mammalian tissues, the metabolism of propionyl-CoA (Fig. 1) involves (i) the formation of (S)-methylmalonyl-CoA by biotin-dependent propionyl-CoA carboxylase ...
Figure 1 from Assessing the Reversibility of the Anaplerotic ...
FIG. 1. Interrelationship between the propionyl-CoA pathway and the CAC in liver and heart. Numbered enzymes are: 1, propionyl-CoA carboxylase; 2, ...
Assessing the reversibility of the anaplerotic reactions of ... - PubMed
Assessing the reversibility of the anaplerotic reactions of the propionyl-CoA pathway in heart and liver ... J Biol Chem. 2003 Sep 12;278(37):34959-65. doi: ...
Assessing the Reversibility of the Anaplerotic Reactions of the ...
FIG. 1. Interrelationship between the propionyl-CoA pathway and the CAC in liver and heart. Numbered enzymes are: 1, propio- nyl ...
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... anaplerosis in micro-organisms was discovered in the 1960s (1),. its importance for the homeostasis of mammalian cells (particu-. larly cardiomyocytes) was ...
Cardiac anaplerosis in health and disease: food for thought - PMC
... anaplerosis in general and/or at a specific site (Figure 1). For example ... Assessing the reversibility of the anaplerotic reactions of the propionyl ...
Investigation of anaplerosis from propionyl-CoA precursors and fatty ...
View All 5 Figures & Tables. 203 References. Filters. Sort by Most Influenced Papers, Sort by Citation Count, Sort by Recency. 1 Excerpt. Assessing the ...
Substrate–Enzyme Competition Attenuates Upregulated Anaplerotic ...
Thus, we have determined partial reversibility of increased anaplerosis in HYP. ... anaplerotic enzymes (see Figure 1). Such an increase in ...
Assessing the reversibility of the anaplerotic reactions ... - Europe PMC
As part of a study on the regulation of anaplerosis from propionyl-CoA precursors in rat livers and hearts, we investigated the degree of reversibility of the ...
Ins and Outs of the TCA Cycle: The Central Role of Anaplerosis
Ins and Outs of the TCA Cycle: The Central Role of Anaplerosis. Melissa Inigo1, Stanisław Deja1,2, and Shawn C. ... Direct assessment of ...
Synthetic anaplerotic modules for the direct synthesis of complex ...
The CETCH cycle revolves around two reductive carboxylation reactions that catalyze two one-carbon extensions (reactions 1 and 7; Fig. 1a).
Imaging brain glucose metabolism in vivo reveals propionate as a ...
28. Reszko, A.E. ∙ Kasumov, T. ∙ Pierce, B.A. ... Assessing the reversibility of the anaplerotic reactions of the propionyl-CoA pathway in heart ...
3.1 Anaplerosis - SpringerLink
The principal anaplerotic carboxylation reactions in the brain are probably those that catalyze carboxylation of pyruvate to malate or oxaloacetate Figure 3.1-1 ...
A 13C Mass Isotopomer Study of Anaplerotic Pyruvate ...
Hearts perfused with 1 mm lactate, 0.2 mmpyruvate, and 0.2 mm octanoate were taken as controls. Statistical significance at p < 0.05 was assessed using a one- ...
Reversible TCA cycle anaplerosis confers resilience to...
(C) Quantification of Purkinje cell density in AAV-transduced loops (one-way ANOVA; n = 3 to 4 mice). Data are presented as means ± SEM; ***P < 0.001. (D) ...
Tricarboxylic acid cycle and anaplerotic enzymes in rhizobia
Additional products shown. Figure 1. Reactions of the TCA cycle. Cycle ... 1.3) catalyzes the reversible isomerization of citrate and isocitrate (Fig. 1) ...
Comprehensive Analysis of C. glutamicum Anaplerotic Deletion ...
... anaplerotic enzymes under these conditions (Figure 1). FIGURE 1. www ... one CO2 as in the case of alternative ME or reversible PEPCk activities. One ...
Anaplerotic pathways in Halomonas elongata - bioRxiv
Figure 1: Anaplerotic reactions and TCA cycle in Halomonas elongata. Shown are the four enzymes PEP carboxylase (PPC, blue), Oxaloacetate ...
Q-Flux: A method to assess hepatic mitochondrial succinate ...
... (Figure 1B),. 14. Brunengraber, H. ∙ Roe ... Figure 2 Assessment of TCA cycle reversibility confirms bidirectional activity of complex II.
Impaired anaplerosis is a major contributor to glycolysis inhibitor ...
1 d-e, and Supplemental Figure S1 for other glycolytic intermediates). Additionally, across glioma cell lines treated with POMHEX in vitro, we ...