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Figure 2. Results of cross|traits meta|analysis by ASSET based on...


Figure 2. Results of cross-traits meta-analysis by ASSET based on...

Cross-trait meta-analysis utilizes summary statistics from multiple large scale genome wide association studies (GWAS) to infer shared disease etiology, and it ...

a large-scale genome-wide cross-trait meta-analysis - PMC

... results of our bidirectional MR analysis is shown in Figure 2. The ... analysis of all candidate SNPs selected based on the results of cross ...

Insights from genome-wide cross-trait analysis

... 2 traits) (Fig 2, C). Population stratification is arguably the only ... Two specific methods, association analysis based on SubSETs (ASSET). 42 ...

Statistical power and utility of meta-analysis methods for cross ...

We specifically focus on three conditions commonly encountered in the studies of multiple traits: (1) extensive heterogeneity of genetic effects ...

GCPBayes: An R package for studying Cross-Phenotype Genetic ...

... effect based on CI`). Study 1 Study 2 Total Pleiotropic effect rs10740997 1 0 1 No rs10764330 1 0 1 No rs10828266 1 0 1 No rs12570400 1 0 1 ...

An efficient Bayesian meta-analysis approach for studying cross ...

It takes into account heterogeneity in the size and direction of the genetic effects across traits. It can be applied to both cohort data and separate studies ...

ASSET: An R package for subset-based association analysis of ...

The package allows the user to search through all possible subsets of z-scores to identify the subset of traits giving the best meta-analyzed z-score. Further, ...

Genome-Wide Large-Scale Multi-Trait Analysis Characterizes ...

Results are shown for only the lead SNPs of 2,293 independent loci identified by fastASSET. Sub-figures show (a) Distribution of number of ...

Cross-asset momentum and the role of hybrid funds - ScienceDirect

1, Fig. 2. The explosive growth of stock-bond hybrid funds is particularly noteworthy, reflecting shifts in investor preferences towards diversified asset ...

Mendelian randomization analyses clarify the effects of height on ...

pruned using a graph-based approach with a greedy approximation algorithm (URLs) using ... Fig 2), a result that was consistent with previous ...

Defining Cross-Asset Decision Making: A Discussion Paper

Figure 2. Pavement conditions declined overall with fewer “very good” miles ... The multiplication of scores based on criteria times the weighting ...

CRR Implementation Guide Asset Management FINAL - CISA

Are services prioritized based on analysis of the potential impact if the ... Figure 2 illustrates an example of how an organization's critical service ...

Axiom™ Genotyping Solution Data Analysis - USER GUIDE

SNPolisher™ package via the Ps_Visualization function, and (2) Axiom™ Analysis Suite via the SNP. Cluster Graph function. ... Figure 19 Effect of ...

ESG AND FINANCIAL PERFORMANCE: - NYU Stern

Rockefeller Asset Management's research shows similar results: one study emphasizes that ESG integration will increasingly be demarcated between “Leaders” and “ ...

Imputation-Based Analysis of Association Studies: Candidate ...

For brevity, we refer to SNPs that affect phenotype as QTNs, for quantitative trait nucleotides. Our prior on the SNP effects has two components ...

ASAP: A Conceptual Model for Digital Asset Platforms

Figure 2: Benefits of leveraging Asset-Platform separation through ... cross-platform case study, can be used to implement multiple asset exchanges. A ...

ESG and financial performance: aggregated evidence from more ...

This study is the first effort to provide aggregated evidence based on more than 2000 empirical studies that have been released since the 1970s (see. Figure 1).

How to build a cross-asset value factor | Lombard Odier

With these settings, we obtained the results shown in table 1 and the indexed performances shown in figure 2. ... 11 and 1.12 depending on the ...

2022 ESG Report: - Morgan Stanley

2 Where Asset Managers ... calculate scope 2 market-based emissions for the 2012 base year as the Firm cannot calculate market-based results for.

Analysis of risk-weighted assets for market risk

Based on the results of this analysis, disclosures ... For this analysis the same definition of trading assets is used as in Figure 2.