Figures and data in The IRE1/XBP1 signaling axis promotes skeletal ...

The IRE1/XBP1 signaling in myofibers is essential for robust skeletal muscle regeneration in response to injury.

The IRE1/XBP1 signaling axis promotes skeletal muscle ... - eLife

There was no significant difference in the numbers of satellite cells between uninjured TA muscle of Ern1fl/fl and Ern1cKO mice (data not shown) ...

The IRE1/XBP1 signaling axis promotes skeletal muscle ... - PubMed

Skeletal muscle regeneration is regulated by coordinated activation of multiple signaling pathways. The unfolded protein response (UPR) is a ...

The IRE1/XBP1 signaling axis promotes skeletal muscle ... - NCBI

There was no significant difference in the numbers of satellite cells between uninjured TA muscle of Ern1fl/fl and Ern1cKO mice (data not shown). However, our ...

(PDF) The IRE1/XBP1 signaling axis promotes skeletal muscle ...

Abstract and Figures ; Research article Cell Biology | Stem Cells and Regenerative Medicine. Roy et al. eLife 2021;0:e73215. DOI: https:// doi.

[PDF] The IRE1/XBP1 signaling axis promotes skeletal muscle ...

The experiments suggest that the IRE1α-mediated signaling promotes muscle regeneration through augmenting the proliferation of satellite cells in a cell ...

The IRE1α/XBP1 signaling axis drives myoblast fusion in adult ...

The IRE1α/XBP1 arm of the unfolded protein response promotes myoblast fusion during skeletal muscle regeneration and overload-induced myofiber hypertrophy.

IRE1/XBP1 signaling promotes skeletal muscle regeneration ...

In the present study, we demonstrate that IRE1α-XBP1 pathway is activated in skeletal muscle of mice upon injury. Myofiber-specific deletion of ...

The IRE1α/XBP1 signaling axis drives myoblast fusion in adult ...

... Signal Activator IRE1 ... (2021) The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.

The IRE1α/XBP1 signaling axis drives myoblast fusion in adult ...

IRE1α signaling in satellite cells promotes skeletal muscle regeneration in adult mice. ... Figure EV1 Source Data (Zip archive, 22.34 MB). Figure EV2 ...

(PDF) IRE1/XBP1 signaling promotes skeletal muscle regeneration ...

the IRE1α/XBP1 pathway in injured muscle (Figure 1A). We next sought to investigate the role of IRE1α in skeletal muscle regeneration. Floxed. Ire1 (henceforth ...

The IRE1α-XBP1 Signaling Axis Promotes Glycolytic ... - ASM Journals

Together, these data demonstrate that IRE1α supports macrophage glycolytic reprogramming in response to inflammatory stimuli. XBP1 supports ...

S-SCDT-10_1038-S44319-024-00197-4 - EMBL-EBI

The IRE1α/XBP1 signaling axis drives myoblast fusion in adult skeletal muscle ; Figure 3.zip, 116.7 MB, Figure 3, Source Data ; Figure 4.zip ...

IRE1/XBP1 and endoplasmic reticulum signaling - ScienceDirect.com

... promote IRE1–XBP1 pathway, [117]. Cab45S, TM, HeLa, Direct binding ... pathways, as extensive crosstalk occurs between all three (Figure 1a).

IRE1α protects against osteoarthritis by regulating progranulin ...

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism. Elife 10, e73215 (2021). Article ...

IRE1α regulates skeletal muscle regeneration through myostatin ...

IRE1α RNase blunts myostatin signaling and promotes myoblast differentiatio Figure 3 ... Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses ...

Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T ...

Quality control of the RNA sequencing data is shown in Additional file 1: Figure S3. Comparing transcriptomes of naïve and activated Th2 ...

Perspective study of UPR signaling molecules as potential ...

Overview of Molecular Markers of IRE1Α-XBP1 Pathway Involved in Bone Metabolism (Table 1). Overexpression of IRE1 ...

Impairment of both IRE1 expression and XBP1 activation is a ...

Key Points. GCB DLBCLs are characterized by a defective IRE1-XBP1 pathway.XBP1 expression reduces GCB DLBCL tumor growth in a mouse xenograft model.

IRE1α–XBP1 signaling in leukocytes controls prostaglandin ...

Activation of the IRE1α–XBP1 pathway in leukocytes promotes PGE2 generation and pain. ER stress, inflammatory conditions, or engagement of ...