Fixed|duration therapy with venetoclax|obinutuzumab in frontline CLL

First-Line Venetoclax Combinations in Chronic Lymphocytic Leukemia

The treatment adherence to the planned number of cycles in each group was high, ranging from 81.5% in the chemoimmunotherapy group to 93.9% in ...

Fixed-Duration Therapy in Frontline CLL: Venetoclax Plus ... - OncLive

Fixed-Duration Therapy in Frontline CLL: Venetoclax Plus Obinutuzumab ... The rationale for investigating the fixed-duration, all-oral combination ...

Fixed-Duration Regimen Safe, Effective for CLL | ASH Clinical News

Patients with previously untreated chronic lymphocytic leukemia (CLL) who receive one-year fixed-duration treatment with venetoclax-obinutuzumab (Ven-Obi) ...

Fixed-Duration Venetoclax plus Obinutuzumab New Standard of ...

... obinutuzumab as front-line therapy in older patients with chronic lymphocytic leukemia (CLL) and comorbidities. The fixed-duration regimen significantly ...

Expert Perspectives on Fixed Duration Therapy with Venetoclax + ...

A panel of experts discuss the role of fixed duration therapy with venetoclax and obinutuzumab, outlining their general approach for patient ...

Venetoclax and Obinutuzumab in Patients with CLL and Coexisting ...

In conclusion, fixed-duration, targeted treatment with venetoclax–obinutuzumab was effective in previously untreated patients with CLL and ...

Acalabrutinib, venetoclax, and obinutuzumab as frontline ... - PubMed

Background: Both continuous therapy with acalabrutinib and fixed-duration therapy with venetoclax-obinutuzumab are effective for previously ...

BTK Inhibitors vs Venetoclax: Considerations for Frontline Treatment ...

In the context of acalabrutinib, it can also be combined with obinutuzumab [Gazyva] for a duration of 6 months. The other approach is a ...

Fixed-Duration Targeted Therapy with Venetoclax plus ...

Based on these results, on May 15, 2019, the FDA approved the combination of venetoclax plus obinutuzumab as frontline treatment for a fixed duration for ...

Venetoclax and obinutuzumab for frontline treatment of chronic ...

... fixed-duration, chemotherapy-free option for patients with previously untreated chronic lymphocytic leukemia (CLL). With the expanding ...

Fixed-Duration, Triple-Combination Therapy Shows Efficacy for ...

The triple combination of obinutuzumab, ibrutinib, and venetoclax has shown a relatively high response rate among previously untreated patients with high-risk ...

CLL14: feasibility of fixed-duration frontline therapy in CLL

The study demonstrated the superiority of venetoclax plus obinutuzumab as well as the feasibility of fixed-duration therapy in these patients.

First-line venetoclax combinations versus chemoimmunotherapy in ...

The planned treatment duration was six cycles in the chemoimmunotherapy group, 12 cycles in the venetoclax–rituximab and the venetoclax– ...

Venetoclax and obinutuzumab for frontline treatment of chronic ...

VO has a fixed duration (12 months) with a goal of inducing MRD− remissions and allowing patients a period of time between therapeutic ...

Fixed-duration therapy with venetoclax-obinutuzumab in frontline CLL

Kirsten Fischer of the University of Cologne, Cologne, Germany, discusses data on a new fixed-duration targeted therapy with venetoclax plus ...

Minimal Residual Disease Dynamics after Venetoclax ...

The CLL14 study has established one-year fixed-duration treatment of venetoclax and obinutuzumab (Ven-Obi) for patients with previously ...

Fixed-Duration Venetoclax Plus Obinutuzumab as First-Line ...

“Fixed-duration targeted therapy combining venetoclax and obinutuzumab can be applied safely in elderly patients with CLL and comorbidities. Our ...

Acalabrutinib Plus Venetoclax Offers PFS Advantage Over Standard ...

Acalabrutinib Plus Venetoclax Offers PFS Advantage Over Standard Therapy in Frontline CLL ... A fixed-duration treatment combining acalabrutinib ...

Frontline Management of CLL in 2021 | JCO Oncology Practice

In both arms, patients received 6 months of obinutuzumab therapy. Those randomly assigned to C + G were prescribed chlorambucil on days 1 and 15 ...

What Is the Best Strategy for Frontline Venetoclax Plus ...

For instance, in CLL13, we focused on patients who were younger and fitter. In that study, the fixed-duration treatment with venetoclax plus ...