Focal Adhesion| and IGF1R|Dependent Survival and Migratory ...

Focal Adhesion- and IGF1R-Dependent Survival and Migratory ...

This resistance mechanism contributes to xenograft tumor cell growth, which is prevented with mTOR plus IGFR inhibitors, supporting this combination as a ...

Focal Adhesion- and IGF1R-Dependent Survival and Migratory ...

Despite sustained inhibition of mTORC1/2 signaling, Akt, a kinase regulating cell survival and migration, regains phosphorylation at its ...

Focal Adhesion- and IGF1R-Dependent Survival and Migratory ...

Molecular Cell, Volume 67. Supplemental Information. Focal Adhesion- and IGF1R-Dependent. Survival and Migratory Pathways Mediate. Tumor Resistance to mTORC1/2 ...

IGF-1 receptor activity in the Golgi of migratory cancer cells depends ...

We found that Tyr 1250 and Tyr 1251 (Tyr 1250/1251 ) were autophosphorylated in a cell adhesion-dependent manner.

Focal Adhesion- and IGF1R-Dependent Survival and Migratory ...

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition. Sang-Oh Yoon, Sejeong Shin, Florian A ...

Focal Adhesion- and IGF1R-Dependent Survival and Migratory ...

Request PDF | Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition | Aberrant signaling by ...

Focal Adhesion- and IGF1R-Dependent Survival and ... - Altmetric

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition. Published in. Molecular Cell, July 2017.

Focal Adhesion- and IGF1R-Dependent Survival and Migratory ...

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition ... migration in some cancer cells are quickly ...

Focal adhesion regulation of cell behavior - ScienceDirect.com

Paxillin can also bind to the α4 integrin subunit, and this interaction inhibits α4β1-dependent cell migration [82], [83]. Paxillin also contributes to the ...

FAK activation is required for IGF1R-mediated regulation of EMT ...

The insulin-like growth factor 1 receptor (IGF1R) and focal adhesion ... cell survival, anti-apoptotic properties, and cell migration.

Functional and clinical characteristics of focal adhesion kinases in ...

Orai3 calcium channel regulates breast cancer cell migration through calcium-dependent and-independent mechanisms. ... Control of adhesion-dependent cell survival ...

Focal adhesion kinase confers pro‐migratory and antiapoptotic ...

Oncogenesis of Ewing sarcoma (EwS), the second most common malignant bone tumor of childhood and adolescence, is dependent on the expression ...

An evolutionary and physiological perspective on cell-substrate ...

... adhesion-mediated processes such as migration, cytokinesis, and cell survival. ... migration through spatiotemporal dynamics of contractility-dependent adhesions ...

Focal Adhesion- and IGF1R-Dependent Survival and Migratory ...

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition. Mol. Cell Pub Date ...

Turnover of Focal Adhesions and Cancer Cell Migration

... survival and migration [19–23]. In particular, two well-characterized tyrosine kinases, focal adhesion kinase (FAK) and Src, play central ...

Governing epidermal homeostasis by coupling cell–cell adhesion to ...

The increased dependency of cells upon matrix interactions for their survival ... The ability to properly coordinate cell survival, adhesion, and migration is ...

Focal Adhesion- and IGF1R-Dependent Survival and Migratory ...

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition. Yoon, Sang-Oh; Shin, Sejeong; Karreth, ...

Inhibition of cell migration by focal adhesion kinase

Furthermore, the time-dependent differences in proteins associated with the integrin-mediated FAK/Rho GTPases signaling pathway within 2 h were ...

Focal adhesion-mediated cell anchoring and migration: from in vitro ...

Some nascent adhesions grow in size, recruit additional proteins and mature into focal adhesions in a myosin II-dependent manner.

Phosphorylated Caveolin-1 Regulates Rho/ROCK-Dependent Focal ...

... Dependent Focal Adhesion Dynamics and Tumor Cell Migration and Invasion ... survival of patients with clinically confined renal cell carcinoma.