Focus on podocytes
Focus on podocytes: diabetic kidney disease and renal fibrosis
An D-Y, Tan J, Lu Y-D, Wen Z-H, Bao Y-N,. Yao Z-H, Chen Z-Y, Wang P-P, Zhou W, Yang Q and Hao M (2024) Focus on podocytes: diabetic kidney ...
Focus on Podocytes: Diabetic Kidney Disease and Renal Fibrosis
Podocytes are crucial due to their dual barrier functions in kidney diseases. Their role in renal fibrosis and DKD regulatory mechanisms is increasingly studied ...
Role of the Innate Immune Response in Glomerular Disease ...
Podocytes, the terminally differentiated ... Role of the Innate Immune Response in Glomerular Disease Pathogenesis: Focus on Podocytes.
Role of the Innate Immune Response in Glomerular Disease ... - MDPI
Role of the Innate Immune Response in Glomerular Disease Pathogenesis: Focus on Podocytes · 1. Introduction · 2. Podocytes in Innate Immunity · 3. Immune Response ...
Fabry nephropathy: focus on podocyte damage and therapeutic target
Fabry disease, a rare X-linked lysosomal storage disorder, is marked by a deficiency in the activity of the enzyme α-galactosidase A. This ...
Podocyte Injury in Diabetic Kidney Disease: A Focus on ... - PubMed
Podocytes are a crucial cellular component in maintaining the glomerular filtration barrier, and their injury is the major determinant in ...
Podocyte - an overview | ScienceDirect Topics
The podocyte is a highly specialized visceral epithelial cell that forms the outermost layer of the glomerular capillary loop.
The podocyte's response to injury: Role in proteinuria and ...
The clinical signature of podocyte injury is proteinuria, with or without loss of renal function owing to glomerulosclerosis.
Podocyte OTUD5 alleviates diabetic kidney disease through ...
The decrease in the number or density of podocytes leads to membrane destruction and promotes proteinuria. Therefore, the degree of podocyte ...
Suleiman Lab - Division of Nephrology - Washington University
Our main focus is podocytes biology, an elaborate-looking cell that is important for the kidney filtration function. Podocytes are unique cells and can be ...
Podocentric view of glomerular proteinuria: Focused on cytoskeletal ...
Among renal cells, podocytes (glomerular epithelial cells) are the most critical to prevent plasma proteins from excessive loss by forming ...
Urinary podocyte markers in kidney diseases - ScienceDirect.com
Podocyte is the primary focus of many kidney diseases. · Podocytes and their microvesicles could be quantified in urine. · They may be used as biomarkers of ...
Inactivation of mediator complex protein 22 in podocytes results in ...
Podocytes are critical for the maintenance of kidney ultrafiltration barrier and play a key role in the progression of glomerular diseases.
The Pathophysiologic Role of Gelsolin in Chronic Kidney Disease
Podocytes play a critical role in maintaining the glomerular filter's integrity and have been the main focus regarding glomerular research for ...
Podocyte injury and its consequences - Kidney International
This review focuses on the cellular aspects of podocyte dysfunction and the adaptive or maladaptive glomerular responses to podocyte injury that lead to its ...
Role of Sphingolipid Signaling in Glomerular Diseases
Changes in the function and number of podocytes can lead to the development and progression of glomerular diseases, including diabetic kidney disease (DKD) and ...
Podocytes as a therapeutic target - JSciMed Central
Podocytes lose their unique structure in the event of a glomerular injury, which is most often associated with podocyte actin cytoskeleton ...
New insights into the immune functions of podocytes: the role of ...
... focusing on the pathogenic link between complement and podocyte damage ... podocytes. Podocyte slit diaphragm, glomerular basement ...
The podocyte as a direct target for treatment of glomerular disease?
A failure to maintain the glomerular filtration barrier directly contributes to the onset of CKD. The visceral epithelial cells, podocytes, are integral to the ...
Role of Podocyte in Kidney Disease - IMR Press
Podocytes are epithelial cells lining the outer surface of the renal glomerular capillaries and they play a pivotal role in maintaining the structural and ...