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Functional genomic screening


Functional genomic screening - Horizon Discovery

Investigate gene/gene interactions, study gene pathways, identify drug targets, interrogate mechanisms of action using functional genomic screening.

Functional Genomics Screening - Sigma-Aldrich

There are two fundamental ways that functional genomics can link genetics to phenotype. Forward genetic screening involves modifying many genes, selecting for ...

A new era in functional genomics screens | Nature Reviews Genetics

In the case of functional genomic screening, systematic perturbations in the form of individual sgRNAs can be coupled with single-cell RNA ...

Functional Genomics Screening Workflow | Thermo Fisher Scientific

Discover gene and protein functions, pathways, and interactions on genome-wide scale in wide variety of model systems.

Functional Genomic Screening Solutions - Revvity

Revvity's wide range of gene editing and modulation solutions are designed to support you in every step of your workflow.

Functional genomics - AstraZeneca

Functional genomics is a rapidly advancing drug discovery method that can be used to explore links between our genes and their effects.

Functional Genomic Screening - Types & Formats of Libraries

High-throughput genetic screening approaches combine libraries of small interfering RNA (siRNA), short hairpin RNA (shRNA), microRNA or CRISPR-Cas9 guide RNA ( ...

Functional Genomics Lab

The Functional Genomics Lab includes a robotic platform with integrated, automated devices for conducting all aspects of screening assays, ...

Functional Genomics Platform | Whitehead Institute

sgRNA library design, cloning, and propagation; Virus preparation for optimization and screening; Vector design; Sequencing library preparation; Data analysis ...

Functional Genomics and High-Throughput Screening

In parallel efforts, we are carrying out studies to reveal the function and action of genes/proteins that are putatively involved in cancer, aging and ...

Integrative analysis of functional genomic screening and clinical ...

We demonstrate that integrative analysis of CRISPR screening datasets enables network-based prioritization of prescription drugs modulating ...

CRISP-view: a database of functional genetic screens spanning ...

Functional genetic screening is a high-throughput, cost-effective technology to identify genes or genomic elements that are pertinent to a ...

CRISPR-based functional genomics screening in human-pluripotent ...

CRISPR-Cas9-based functional genomics screening offers a powerful approach to determine gene function in a high-throughput manner. With the ...

Functional Genomics Screening - Webinars - Sigma-Aldrich

Multi-target screening can offer great insight into the genetic pathways involved in drug resistance and disease.

Functional genomic screening in Komagataella phaffii enabled by ...

Comparative analysis of the called gene sets identified a core set of K. phaffii essential genes, many of which relate to metabolic engineering targets, ...

Collaborate with the functional genomics screening laboratory - UKRI

Funding opportunity: Collaborate with the functional genomics screening laboratory ... Apply to collaborate with the functional genomics screening ...

Functional genomic screening in Komagataella phaffii enabled by ...

The high activity, genome-wide CRISPR library developed here enables functional genomic screening in K. phaffii, applied here to gene essentiality ...

Functional Genomic Screening: A Brief History | Biocompare

Functional genomics arose in the post-genome era to use and understand the massive amount of sequencing data in a biological context, and ...

Functional Genomic Screening Services - Revvity

Functional genomic screening for target identification. Expand your gene perturbation with high-throughput screening capabilities. A functional genomic approach ...

Functional genomic screening approaches in mechanistic toxicology ...

CRISPR-Cas9 is a powerful and flexible functional genomic screening approach that can be harnessed to provide unprecedented mechanistic insight in the field of ...