GWAS meta|analysis reveals dual neuronal and immunological ...

GWAS meta-analysis reveals dual neuronal and immunological ...

GWAS meta-analysis reveals dual neuronal and immunological etiology for pain susceptibility ... This article is a preprint and has not been peer- ...

GWAS meta-analysis reveals dual neuronal and immunological ...

These analyses double the number of known risk loci for pain susceptibility and support dual causation from neuronal and immunological genes, ...

GWAS meta-analysis reveals dual neuronal and immunological ...

These analyses double the number of known risk loci for pain susceptibility and support dual causation from neuronal and immunological genes, providing leads ...

Genome wide association joint analysis reveals 99 risk loci for pain ...

4e-20) (Table O in S1 Data). These results support dual neurological and immunological etiology for pain susceptibility. Genetic effects in pain ...

GWAS meta-analysis of over 29,000 people with epilepsy identifies ...

... neurons in the brain. Prioritized candidate ... The FE analysis did not reveal any genome-wide significant signals. ... Single asterisk indicates ...

GWAS Meta-Analysis Reveals Shared Genes and Biological ...

The heritability of MDD is 40% to 50% suggested by twin studies [11]. ... Sub-cell type analysis revealed that such cerebellar neurons ... immune-related, (epi) ...

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue ...

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets ... twin studies (Deary et ...

GWAS meta-analysis reveals key risk loci in essential tremor ...

... analysis, and reveals key roles of dopaminergic and GABAergic neurons in the pathogenesis ... Antiepileptic Drugs and Their Dual Mechanism ...

Omics approaches to discover pathophysiological pathways... - PAIN

The most recent GWAS meta-analysis on 17 pain susceptibility traits reveals equal neuronal and immunological etiology for pain susceptibility. 51. Further ...

GWAS_lit on X: "GWAS meta-analysis reveals dual neuronal and ...

GWAS meta-analysis reveals dual neuronal and immunological etiology for pain susceptibility https://t.co/kcjhTjzo1I.

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue ...

Reveals Tissue-Specific Neural Expression ... greater, as determined by both classical twin studies (Deary ... GTEX tissue expression, IMMGEN immune ...

A genome‐wide association meta‐analysis of all‐cause and ...

Interestingly, the GWAS-PW approach additionally reveals the shared genetic susceptibility of VaD with IS and WMH at the PRPF8 and PRDM6 locus.

Integrating single-cell sequencing data with GWAS summary ...

Single-cell RNA sequencing (scRNA-seq) has been extensively utilized to reveal the immune responses of COVID-19 patients in both lung and ...

Genome-wide analyses of individual differences in ... - PNAS

Decades of family and twin studies have revealed substantial genetic components contributing to individual variation in reading- and language-related traits ...

Large-scale cognitive GWAS Meta-Analysis Reveals Tissue-Specific ...

Large-scale cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets ... twin studies and ...

The complex genetic architecture of Alzheimer's disease: novel ...

... twin studies and a downward bias in SNP-heritability estimates. By incorporating genetic information from GWAS into twin study heritability ...

Genome-wide association meta-analysis identifies 48 risk variants ...

Locus annotation: single dash (-), <100 kb; double dash (--), 100–500 kb; triple dash (---), >500 kb. b. No previous association with hearing loss in a GWAS.

Multivariate GWAS of psychiatric disorders and their cardinal ...

Biological annotation revealed divergent genetic architectures that differentially implicated prenatal neurodevelopment and neuronal function ...

A large-scale genome-wide association study meta-analysis of ...

To conduct this GWAS meta-analysis of cannabis use disorder and identify associations with genetic loci, we used samples from the Psychiatric ...

GWAS meta-analysis (N=279,930) identifies new genes ... - bioRxiv

Associated genes are strongly expressed in the brain and specifically in striatal medium spiny neurons and cortical and hippocampal pyramidal ...