Gastrointestinal Symptoms in 342 Patients With Fabry Disease

Gastrointestinal symptoms in 342 patients with Fabry disease

The gastrointestinal symptomatology of Fabry disease is very similar to diarrhea-predominant IBS; however, pathophysiologic similarities remain to be ...

Gastrointestinal Symptoms in 342 Patients With Fabry Disease: Prevalence and Response to Enzyme Replacement Therapy. BJOERN HOFFMANN,* MARTIN SCHWARZ,‡ ATUL ...

Gastrointestinal Symptoms in 342 Patients With Fabry Disease

Results: The overall prevalence of gastrointestinal symptoms was 52%, with abdominal pain and diarrhea being most frequent. Female patients were more frequently ...

Gastrointestinal Symptoms in 342 Patients With Fabry Disease

1. ... 2. ... The biochemical consequence is a progressive lysosomal accumulation of globotriaosylceramide in nearly all organ systems. The clinical ...

Gastrointestinal symptoms in Fabry disease - PubMed

The Fabry Outcome Survey (FOS) database supports these observations. The overall prevalence of gastrointestinal involvement reported in a study of 342 patients ...

Gastrointestinal symptoms in Fabry disease: everything is possible ...

The overall prevalence of gastrointestinal involvement reported in a study of 342 patients (271 adults; 71 children) enrolled in FOS was 52 ...

Gastrointestinal involvement in Fabry disease. So important yet often ...

Fabry Outcome Survey. European Investigators. Gastrointestinal symptoms in 342 patients with. Fabry disease: prevalence and response to enzyme replacement ...

Fabry disease – a multisystemic disease with gastrointestinal ...

In patients with a long-term history of unexplained GI symptoms including postprandial abdominal pain, diarrhea, early satiety, gastroparesis, or chronical ...

Gastrointestinal Symptoms of Patients with Fabry Disease

The most commonly reported GI symptom in affected patients is diarrhoea with frequent loose bowel movements and cramping abdominal pain. In many ...

Non-specific gastrointestinal features: Could it be Fabry disease?

Non-specific gastrointestinal symptoms, including pain, diarrhoea, nausea, and vomiting, can be the first symptoms of Fabry disease.

Gastrointestinal Involvement in Anderson-Fabry Disease - MDPI

GI symptoms are very common in FD, affecting up to 50% of female patients and almost 60% of untreated children [4,30,31,32], according to the ...

Gastrointestinal symptoms in 342 patients with Fabry disease

TL;DR: The gastrointestinal symptomatology of Fabry disease is very similar to diarrhea-predominant IBS; however, pathophysiologic similarities remain to be ...

Genetic variants associated with gastrointestinal symptoms in Fabry ...

Post-prandial abdominal pain and diarrhea are the most prevalent manifestations, while less common GIS include nausea, vomiting, and early ...

Understanding the gastrointestinal manifestations of Fabry disease

The most common complaint and often the initial GI symptom is abdominal pain affecting up to one third of patients [Hoffmann et al. 2007]. Patients describe ...

How Cystic Fibrosis and Fabry Disease Affect the Gut

Gastrointestinal symptoms can be amongst the first to present in individuals with Fabry disease. In the European Fabry Outcome Survey of 342 ...

Understanding the gastrointestinal manifestations of Fabry disease

(2007) Gastrointestinal symptoms in 342 patients with Fabry disease: prevalence and response to enzyme replacement therapy. Clin Gastroenterol. Hepatol 5 ...

Gastrointestinal Sensory Neuropathy and Dysmotility in Fabry Disease

In 48 patients with Fabry disease, abnormal bowel habits and abdominal pain were the most common symptoms. Bloating, nausea, vomiting, and reflux were also ...

Gastrointestinal Manifestations and Treatment Options in Fabry ...

Gastrointestinal symptoms in 342 patients with Fabry disease: prevalence and response to enzyme replacement. Page 8. Gastrointestinal ...

Fabry Disease Gastrointestinal Symptoms

Gastrointestinal (GI) symptoms are a common symptom among individuals with Fabry disease and they can have a very disruptive impact on living a normal ...

A new Fabry disease-specific gastrointestinal outcomes instrument

Among the GI signs and symptoms reported by ≥50% of patients (diarrhea, bloating, constipation, and cramping), mean bother ratings ranged from ...