Gender|Based Differences in Autoimmunity and Autoimmune Disease

Gender differences in autoimmune disease - PubMed

Autoimmune diseases are a range of diseases in which the immune ... Keywords: Autoimmunity; Gender; Immune system; Sex differences.

Sex and gender influence on immunity and autoimmunity - Frontiers

Females predominate with most autoimmune diseases. The reasons for this predilection are an interplay of genetic, epigenetic and hormonal factors.

Understanding sex differences in autoimmune disease

Four of every five people diagnosed with an autoimmune disease are female. Researchers have been looking for differences in genes and hormones that may explain ...

Stanford Medicine-led study shows why women are at greater risk of ...

Research throws light on the mystery of why women are much more prone to autoimmune disorders: A molecule made by one X chromosome in every female cell can ...

Sex-based differences in autoimmune diseases - ISS

Autoimmune disease and gender: Plausible mechanisms for the female predomi- nance of autoimmunity. J Autoimmun 2012;38(2-3):J109-. 19. DOI: 10.1016/j.jaut ...

Gender differences in autoimmune disease - ScienceDirect.com

The gender differences in autoimmunity could be due to differences between male and female immune systems (McCombe and Greer, 2013a). Such differences are found ...

Mechanisms underlying sex differences in autoimmunity - JCI

What constitutes an autoimmune disease depends on how they are defined (6), with the number of autoimmune diseases varying from 80 to 120 or ...

Why women have more autoimmune diseases than men

Several facts suggest differences in antibodies may cause increased prevalence of autoimmune disease in women. First, the association between ...

Center for Sex-based Differences in the Immune System

Women are better at fighting off infection but are more likely to develop an autoimmune condition, with 80 percent of autoimmune disease cases diagnosed in ...

A Gender Gap in Autoimmunity - Science

The predominance of autoimmune disease among women suggests that sex hormones may modulate susceptibility. Most attention has been directed toward the sex ...

Why are autoimmune diseases more prevalent in women?

In recent years it has become clear that the X chromosome plays an important part in the development of autoimmunity (5). The purpose of this ...

Why autoimmune disease is more common in women: X ... - Nature

A new explanation for the discrepancy has emerged: a molecular coating typically found on half of a woman's X chromosomes — but not in males' ...

Mechanisms of sex hormones in autoimmunity: focus on EAE

Sex-related differences in the occurrence of autoimmune diseases is well documented, with females showing a greater propensity to develop ...

"There are dramatic gender differences" | Karolinska Institutet

Nils Landegren is a doctor and researcher specialising in autoimmunity. He has started a research project to investigate why autoimmune diseases are so much ...

Gender differences in autoimmunity associated with exposure to ...

▻ Gender is a significant risk factor with many autoimmune diseases. ▻ Increased risk of autoimmunity is influenced by gender biased activities. ▻ Gender bias ...

How Sex & Genetics Influence Autoimmunity

However, research has shown that there are differences in autoimmune disease symptoms and diagnosis between males and females, which can impact ...

Sex differences in immune responses | Nature Reviews Immunology

Autoimmune diseases. Women represent ∼80% of all cases of autoimmunity in the US. Sex differences in the incidence of autoimmunity are most ...

Autoimmune Disease in Women: Endocrine Transition and Risk ...

The “gender gap” in autoimmunity has been well known for over 20 years (10, 11) and AI diseases are a leading cause of death among young and middle-aged women ( ...

Sexual dimorphism in autoimmunity - JCI

Most autoimmune diseases predominantly affect females, indicating a strong sex bias. Various factors, including sex hormones, the presence or absence of a ...

Immune response and autoimmune diseases: a matter of sex

Accordingly, most autoimmune diseases are more prevalent in women than in men and symptoms, disease course and response to therapy may also differ between males ...