Genetic Testing for Statin|Induced Myopathy

GENETIC TESTING FOR STATIN-INDUCED MYOPATHY

Commercially Available SLCO1B Molecular Diagnostic Tests. Several commercial and academic labs offer genetic testing for statin-induced myopathy.

Genetic Testing May Improve Statin's Ability to Lower Cholesterol

A commercially available genetic test can identify patients likely to be more susceptible to statin myopathy and guide physician prescription choices to ...

Genetic Testing for Statin-Induced Myopathy - Bynder

Genetic testing for the presence of variants in the SLCO1B1 gene to identify patients at risk of statin-induced myopathy is considered not ...

Role of genetics in the prediction of statin-associated muscle ...

A score based on the number of risk alleles in three candidate genes, COQ2, ATP2B1, and DMPK, has been shown to provide good discrimination between patients ...

Muscle problems caused by statins: Can a genetic test reveal your ...

What exactly does StatinSmart measure? Using genetic material from a small sample of your saliva, the test analyzes a gene called SLCO1B1.

Boston Heart Statin Induced Myopathy (SLCO1B1) Genotype Test

The SLCO1B1 gene is critical to the body's uptake and metabolism of statins, drugs prescribed to reduce LDL-C levels for the prevention of heart attacks or ...

Statin-Induced Myopathy - Asper Biogene

Statin-Induced Myopathy targeted mutation analysis ... The A260/A280 ratio should be 1.8-2.0. DNA sample should be run on an agarose gel as a single band, showing ...

Effect of Pharmacogenetic Testing for Statin Myopathy Risk vs Usual ...

One well-described pharmacogenetic association is that between the solute carrier organic anion transporter family member 1B1 (SLCO1B1) gene and ...

Effect of Pharmacogenetic Testing for Statin Myopathy Risk vs Usual ...

Clinical testing and reporting of SLCO1B1 results for statin myopathy risk did not result in poorer ASCVD prevention in a routine primary care ...

Genetic Testing for Statin-Induced Myopathy - Capital Blue Cross

Genetic testing for the presence of variants in the SLCO1B1 gene to identify members at risk of statin-induced myopathy is considered not ...

Genetic Test: Statin-Induced Myopathy (SLCO1B1)

Commercially available tests for the presence of SLCO1B1 variants are currently marketed for use in predicting the risk of myopathy for patients taking statins.

Genetic Testing for Statin-Induced Myopathy | EmblemHealth

Genetic testing of variants in the SLCO1B1 gene to identify individuals at increased risk of statin-induced myopathy is considered ...

SLCO1B1 Variants and Statin-Induced Myopathy — A Genomewide ...

SLCO1B1 encodes the organic anion–transporting polypeptide OATP1B1, which has been shown to regulate the hepatic uptake of statins. The noncoding rs4363657 SNP ...

Test Definition: SLC1Q - Mayo Clinic Laboratories

Presence of the. *5 allele is associated with an increased risk for simvastatin-associated myopathy. Special Instructions. • Informed Consent for Genetic ...

Genomewide Association Study of Statin‐Induced Myopathy in ...

☑ Risk of statin-induced myopathy is associated with variation of the SLCO1B1 gene, which encodes the OATP1B1 hepatic uptake transporter, of ...

A systematic review and meta-analysis of genotype-based ... - Nature

Two polymorphisms (rs2306283 and rs4149056) of SLCO1B1 gene have been reportedly associated with statin and risk of myopathy in statin users, as ...

SLCO1B1 Polymorphisms and Statin-Induced Myopathy

There is a need for studies comparing the clinical validity of SLCO1B1 rs4149056 genotyping with risk scores for myopathy based on other factors ...

Pharmacogenomic Study of Statin-Associated Muscle Symptoms in ...

Muscle symptoms (eg, myalgia and myopathy) are among the most common adverse events associated with statin use and are collectively referred to ...

Medical Policy Genetic Testing for Statin-Induced Myopathy - AAPC

Genetic testing for the presence of variants in the SLCO1B1 gene for the purpose of identifying patients at risk of statin-induced myopathy is considered NOT ...

Pharmacogenomics of statins: understanding susceptibility to ...

However, SLCO1B1 521C is currently the only clinically relevant pharmacogenetic test regarding statin toxicity, and its relevance is limited to ...