Genetic influences on circulating retinol and its relationship ...

Genetic influences on circulating retinol and its relationship ... - Nature

This study provides a comprehensive evaluation of the genetics of circulating retinol, as well as revealing traits which should be prioritised for further ...

Genetic influences on circulating retinol and its relationship to ...

Retinol is a fat-soluble vitamin that plays an essential role in many biological processes throughout the human lifespan.

Genetic influences on circulating retinol and its relationship to ...

This study provides a comprehensive evaluation of the genetics of circulating retinol, as well as revealing traits which should be prioritised for further ...

Genetic influences on circulating retinol and its relationship to ...

Conversely, circulating retinol may be causally influenced by factors including lipids and serum creatinine. Finally, we demonstrate how a retinol polygenic ...

Largest genetic study on circulating retinol reveals new insights into ...

The analysis revealed causal effects of retinol on several clinical phenotypes, including inflammation, adiposity, ocular measures, the ...

(PDF) Genetic influences on circulating retinol and its relationship to ...

Previous work has characterised genetic influences on circulating retinol; however, small sample sizes have limited our ability to fully ...

Genome-wide association study of circulating retinol levels - PMC

The two highly significant SNPs from chromosome 10 were in the gene neighborhood of the RBP4 gene, which encodes retinol-binding protein 4 (RBP4), one of the ...

New research investigates the genetic influences to health of ...

"We can use the genetic variation that influences retinol as a proxy for levels of the vitamin in large genetic studies in millions of ...

New research investigates the genetics of circulating vitamin A

We essentially matched retinol levels with variation in genes to give us a better understanding of the genes involved in retinol absorption and ...

Genetic influences on circulating retinol and its relationship to ...

Genetic proxies of circulating retinol were then used to estimate causal relationships with almost 20,000 clinical phenotypes via a phenome-wide Mendelian ...

Genetic influences on circulating retinol and its relationship ... - OUCI

Genetic proxies of circulating retinol were then used to estimate causal relationships with almost 20,000 clinical phenotypes via a phenome-wide Mendelian ...

Genetic influences on circulating retinol and its relationship to ...

Retinol is a fat-soluble vitamin that plays an essential role in many biological processes throughout the human lifespan. Here, we perform the largest.

Genetic influences on circulating retinol and its relationship to ...

Genetic influences on circulating retinol and its relationship to human health. Author: WR Reay, DJ Kiltschewskij, MA Di Biase, ZF Gerring, et al. Year ...

Genetic influences on circulating retinol and its - ProQuest

Genetic proxies of circulating retinol were then used to estimate causal relationships with almost 20,000 clinical phenotypes via a phenome-wide Mendelian ...

Genetic determinants of retinol circulation and their impact on health

The primary meta-analysis (METSIM+INTERVAL) identified eight significant genetic loci linked to circulating retinol. Notably, six of these loci ...

Genetic influences on circulating retinol and its relationship to ...

Retinol is a fat-soluble vitamin that plays an essential role in many biological processes throughout the human lifespan. Here, we perform the largest ...

Genetic influences on circulating retinol and its relationship ... - OUCI

Conversely, circulating retinol may be causally influenced by factors including lipids and renal function. Finally, we demonstrated how a retinol polygenic ...

Murray Cairns on LinkedIn: Genetic influences on circulating retinol ...

Very pleased to reshare Dr William Reay's post that our paper reporting on the largest ever genome wide association study of circulating retinol was ...

Genetic influences on circulating retinol and its relationship ... - X-MOL

Genetic influences on circulating retinol and its relationship to human health. Nat. Commun. Pub Date : 2024-02-19. DOI : 10.1038/s41467-024-45779-x.

Genetic influences on circulating retinol and its relationship to ...

The MR-pheWAS suggests that retinol may exert causal effects on inflammation, adiposity, ocular measures, the microbiome, and MRI-derived brain phenotypes, ...