Genetics and Gene Expression Involving Stress and Distress ...

Genetics of stress response and stress-related disorders - PMC

The major findings regarding the genetics of stress response and stress-related disorders are: (i) variations in genes involved in the sympathetic system or ...

Stress Hormone Causes Epigenetic Changes

Chronic exposure to corticosterone altered the expression of 3 HPA axis genes, including higher levels of Fkbp5 in the hippocampus, hypothalamus ...

The Genetics of Stress-Related Disorders: PTSD, Depression, and ...

Nominally significant associations have been reported between PTSD symptoms and other neurotransmitter- and neuropeptide-related genes including ...

Differential interactions between gene expressions and stressors ...

Overall, significant interactions between genes by stressors were consistently higher in the brain tissues. In particular, for threat, a higher ...

Genetic Variants Associated With Anxiety and Stress-Related ...

Conclusions and Relevance This study highlights anxiety and stress-related disorders as complex heritable phenotypes with intriguing genetic ...

Epigenetic Modifications in Stress Response Genes Associated With ...

In the hippocampus, total GR expression, and the 1B,1C, 1H GR RNA variant levels decreased with history of childhood trauma. Site-specific methylation showed ...

A gene expression atlas for different kinds of stress in the mouse brain

Adaptations in the brain, mediated by changes in gene expression, have a crucial role in the stress response. Recent years have seen a ...

Chronic stress induces significant gene expression changes in the ...

Adult hippocampal neurogenesis is involved in stress-related disorders such as depression, posttraumatic stress disorders, as well as in the ...

Effects of early- and mid-life stress on DNA methylation of genes ...

Exposure to stress can modify DNA methylation, which may alter gene expression and therefore contribute to disease phenotypes [15]. Early-life ...

Gene expression profiling reveals a role of immune system and ...

Innate and stress-induced anxiety are regulated at least partially by the same brain regions, including the frontal cortex (FCx) and hippocampus ...

From genetics to systems biology of stress-related mental disorders

Network analysis of these differentially expressed genes showed that dysregulated neuroinflammation and immune signalling are involved in both PTSD and MDD ( ...

Gene expression profiling in the stress control brain region ...

This study aims at the identification of genes that are directly or indirectly responding to stress. Inbred mouse strains that had been ...

Epigenetics of Depression: Psychological Stress Alters DNA

In addition to changing gene expression in the short term, psychological stress can impart lasting changes to your DNA by modifying the ...

Gene expression in cord blood links genetic risk for ... - bioRxiv

Co-expression network analysis identified distinct gene expression perturbations across maternal diagnoses, including two depression-related ...

Early stress evokes temporally distinct consequences on the ...

(c) In contrast, middle-aged ES animals revealed a significant regulation of genes involved in ion binding, transcriptional regulation, cellular projection, ...

Childhood stress leaves lasting mark on genes - UW–Madison News

The team also looked at how genes were expressed. In all, more than 1,400 genes showed a difference in expression connected to the amount of ...

How Stress Could Affect Your Genes - Greater Good Science Center

Discrimination is a form of stress—and it may lead to gene expression that puts you at higher risk of disease ...

Early-life social connections influence gene expression, stress ...

Strong social connections and greater maternal care early in life can influence molecular markers related to gene expression in DNA and future stress response.

How genes and life events affect mood and depression

For example, several genes influence the stress response, leaving us more or less likely to become depressed in response to trouble. Perhaps the ...

Chronic stress puts your health at risk - Mayo Clinic

Genetics. The genes that control the stress response keep most people at a fairly steady emotional level, only sometimes priming the body for fight or flight.