Genetics brings new insight to β|cell function

Genetics brings new insight to β-cell function | Nature Metabolism

Genetics brings new insight to β-cell function ... A meta-analysis of genome-wide association study for eight traits related to pancreatic β-cell ...

Genetics brings new insight to β-cell function - PubMed

Genetics brings new insight to β-cell function.

Genetics brings new insight to β-cell function - CoLab

Conclusions:This study in healthy, glucose-tolerant humans shows for the first time different ABS rates during OGTT in women and men and a ...

The pancreatic β cell: recent insights from human genetics - PMC

Human genetics has proven a powerful instrument to explore the genetics of β cell dysfunction. Substantial progress has been made from studies into Mendelian ...

Nature Metabolism

Genetics brings new insight to β-cell function. A meta-analysis of genome-wide association study for eight traits related to pancreatic β-cell function ...

Genetics brings new insight to β-cell function - OUCI

Genetics brings new insight to β-cell function. https://doi.org/10.1038/s42255-024-01131-7. Journal: Nature Metabolism, 2024, № 10, p. 1848-1849. Publisher ...

β-cell neogenesis: A rising star to rescue diabetes mellitus

The molecular mechanisms of β-cell failure engage multiple biological processes such as genetic susceptibility, endoplasmic reticulum (ER) stress, oxidative ...

Pancreas gene finding gives new insights into human development ...

Beta cells within the pancreas produce insulin that regulate blood sugar. Every mammal needs the pancreatic beta-cells to survive. In ...

Systematic single-cell analysis provides new insights into ...

Diabetes mellitus is characterized by loss or dysfunction of insulin-producing β-cells in the pancreas, resulting in failure of blood glucose regulation and ...

Study finds how a genetic variant raises diabetes risk through an ...

... new insights into diseases with relevance to the region. ... gene, relevant cell type, and cellular functions in individuals with MONW.

Loss of ZNF148 enhances insulin secretion in human pancreatic β ...

We (26) recently discovered a link between insulin secretion and a locus that includes the mouse ortholog Zfp148 in a genetic screen performed ...

On knowing a gene: A distributional hypothesis of gene function

However, this approach to understanding genes presents several areas that could benefit from improvement. First, gene sequence discovery far ...

A new wrinkle in turtles: Their genomes fold in a unique way ...

The shape and location of chromosomes during the post-division interphase of the cell cycle impacts gene function because it brings non-adjacent ...

Researchers flip genes on and off with AI-designed DNA switches

... gene in different cell types. Their new approach opens the possibility of controlling when and where genes are expressed in the body, for ...

How does gene therapy work?: MedlinePlus Genetics

Instead of adding new genetic material, genome editing introduces gene-editing tools that can change the existing DNA in the cell. Genome ...

Surprise discovery shakes up our understanding of gene expression

It could induce global chromatin change and affects transcription of 6,000 genes in the cell line we studied. ... UChicago offers new master's ...

GTEx Consortium releases fresh insights into how DNA differences ...

For instance, Ardlie noted, QTL analysis provides only one lens through which to view the functional implications of genetic variation, one that ...

How do genes direct the production of proteins? - MedlinePlus

The journey from gene to protein is complex and tightly controlled within each cell. It consists of two major steps: transcription and translation.

Press release: The Nobel Prize in Physiology or Medicine 2024

They discovered microRNA, a new class of tiny RNA molecules that play a crucial role in gene regulation. ... understanding how different cell ...

The neXt generation of single cell RNA-seq: An introduction to GEM ...

Our new, advanced GEM-X technology provides a robust foundation for ... GEM-X provides higher sensitivity for genes that matter and may ...