Genome|Wide Association Study of Lung Function Phenotypes in a ...

Genome-wide association study of lung function phenotypes in a ...

This study identifies genome-wide significant associations and replicates results of previous GWASs. Multimarker modeling implicated for the first time ...

Genome-Wide Association Study of Lung Function Phenotypes in a ...

Genome-wide association study of lung function phenotypes in a founder population. Tsung-Chieh Yao, Tsung-Chieh Yao, MD, PhD.

Genome-wide association study of lung function phenotypes in a ...

We sought to identify single nucleotide polymorphisms (SNPs) associated with lung function. Methods. We performed a genome-wide association study (GWAS) of FEV1 ...

Genome-wide association study of lung function phenotypes in a ...

This study identifies genome-wide significant associations and replicates results of previous GWASs. Multimarker modeling implicated for the first time common ...

Genome-wide association study of lung function phenotypes in a ...

Results. Our GWAS identified significant associations between FEV1/FVC and SNPs at the THSD4-UACA-TLE3 locus on chromosome 15q23 (P = 5.7 × 10−8 to 3.4 × 10−9).

Genome-wide association study of lung function phenotypes in a ...

Our GWAS identified significant associations between FEV1/FVC and SNPs at the THSD4-UACA-TLE3 locus on chromosome 15q23 (P = 5.7 × 10−8 to 3.4 × 10−9). Nine ...

Genome-wide association study of lung function phenotypes in a ...

Objective We sought to identify single nucleotide polymorphisms (SNPs) associated with lung function. Methods We performed a genome-wide association study (GWAS) ...

Genome-wide association study of lung function phenotypes in a ...

Genome-wide association study of lung function phenotypes in a founder population. J Allergy Clin Immunol. 2014; 133(1):248-55.e1-10. 2014. https ...

Multi-ancestry genome-wide association analyses improve ... - Nature

Through the largest global assembly of lung-function genomics studies to date we: (1) undertook a multi-ancestry GWAS meta-analysis of lung- ...

Genome-wide association study of lung function phenotypes in a ...

Genome-wide association study of lung function phenotypes in a founder population. J Allergy Clin Immunol. 2014 Jan; 133(1):248-55.e1-10. View in: PubMed.

A genome-wide association study identifies distinct variants ... - Nature

In addition to the 110 variants in Europeans previously reported to be associated with phenotypes related to pulmonary function, we identify 279 ...

A Genome-Wide Association Study of Pulmonary Function ... - PLOS

We examined the relationship between common genetic variants and measures of lung function in a sample of 7,691 participants from the Framingham Heart Study and ...

Genome-wide association study of preserved ratio impaired ...

... phenotypes to maximise discovery of heritable genetic variants of lung function and disease. Genetic correlation and PheWAS studies showed there are shared ...

Loci Identified by Genome-wide Association Studies Influence ...

... Phenotypes in Chronic Obstructive Pulmonary Disease ... Genome-wide association study identifies five loci associated with lung function.

Genome-Wide Association Analysis of Rapid Decline in Lung Function

However, the associations between specific genetic variants (single-nucleotide polymorphisms; SNPs) and this phenotype remain uncertain. Methods ...

Genome-wide association study of lung function phenotypes in a ...

Genome-wide association study of lung function phenotypes in a founder population · Tsung-Chieh Yao · Gaixin Du · Lide Han · Ying Sun · Donglei Hu · James J. Yang ...

Exploring the genetics of airflow limitation in lung function across the ...

The most recent and largest genome-wide association study (GWAS) of susceptibility for COPD in adults (n = 257,811) identified a total of 82 independent single ...

Genome-wide Association Study of Pulmonary Function ... - medRxiv

In addition to 377 variants in Europeans previously reported to be associated with phenotypes related to pulmonary function, we identified 330 ...

Genetic insights into lung function inform better management of ...

... associations study (PheWAS), which assesses the association between GRS and a wide range of phenotypes simultaneously. In this study, PheWAS ...

Genome-wide association study of lung function and clinical ...

The aim of this study is to identify genetic loci associated with post-bronchodilator FEV 1 /FVC and FEV 1 , and develop a multi-gene predictive model for lung ...