Genome|wide association analyses of posttraumatic stress disorder ...

Genome-wide association analyses of post-traumatic stress disorder ...

There is a substantial heritable basis for PTSD risk, and evidence from genome-wide association studies (GWAS) shows that PTSD, like other ...

Genome-wide association analyses of post-traumatic stress disorder ...

We conducted genome-wide association analyses of over 250000 participants of European (EUR) and African (AFR) ancestry from the Million Veteran Program ...

Genome-wide association analyses identify 95 risk loci and provide ...

While twin and genetic studies demonstrated that the risk of developing PTSD conditional on trauma exposure is partly driven by genetic factors, ...

Genome-wide association analyses identify 95 risk loci and provide ...

Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders.

Genome-wide Association Studies of Posttraumatic Stress Disorder ...

We performed a meta-analysis of the results for SNP rs159572 on chromosome 5 between 3 GWAS of African American military samples, including data ...

Genome-wide Association Analyses Identify 95 Risk Loci ... - COGA

Post-traumatic stress disorder (PTSD) is a mental health condition that can develop after experiencing a traumatic event.

A genome-wide association study of post-traumatic stress disorder ...

From this analysis, 491 individuals with a history of trauma exposure and valid genotype data were identified as having primarily white non- ...

Genome-Wide Association Study Of Posttraumatic Stress Disorder ...

To achieve the goal, we conducted a GWAS on the severity of three PTSD symptom domains in two US Army cohorts. Methods. We performed genome-wide analysis in two ...

A Genome-Wide Association Study and Polygenic Risk Score ...

We performed a genome-wide association study (GWAS) meta-analysis to identify genetic variants associated with PTSD, and determined if PTSD polygenic risk ...

An epigenome-wide association study of posttraumatic stress ...

The analysis of blood samples yielded one genome-wide significant association with PTSD at cg19534438 in the gene G0S2.

Genome-wide Association Study Identifies New Susceptibility Loci ...

Candidate gene association studies have identified few genetic variants that contribute to PTSD risk. Methods. We conducted genome-wide association analyses in ...

Genome-wide Association Studies of Posttraumatic Stress Disorder ...

The primary analysis compared lifetime DSM-IV PTSD cases with trauma-exposed controls without lifetime PTSD. Data were analyzed from March 18 to ...

Genome-Wide Association Study of Post-Traumatic Stress Disorder ...

Although no variants were significantly associated after correction for multiple testing in a meta-analysis of the two cohorts, pathway analysis of the top hits ...

Genome-wide association analyses of post-traumatic stress disorder ...

Genomic structural equation modeling indicated tight coherence of a PTSD symptom factor that shares genetic variance with a distinct internalizing (mood-anxiety ...

International meta-analysis of PTSD genome-wide association ...

In a multi-ethnic cohort including over 30,000 PTSD cases and 170,000 controls we conduct a genome-wide association study of PTSD. We demonstrate SNP-based ...

Enhancing Discovery of Genetic Variants for Posttraumatic Stress ...

Stress Disorders, Post-Traumatic; Psychiatry; Polymorphism, Single Nucleotide; Phenotype; Humans; Genome-Wide Association Study; Genetic Predisposition to ...

Genome-wide association study of post-traumatic stress disorder ...

We performed a genome-wide association study and bioinformatic analyses, which included 146,660 European Americans and 19,983 African Americans ...

Post-Traumatic Stress Disorder Risk Loci, Candidate Genes Found ...

By bringing in transcriptome-wide association study data, together with a Mendelian randomization analysis that hinged on brain gene expression ...

Genome-wide association analyses of post-traumatic stress disorder ...

Nievergelt, C. M. et al. International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nat.

Genome-wide association analyses of post-traumatic stress disorder ...

These results validate the biological coherence of the PTSD syndrome, inform its relationship to comorbid anxiety and depressive disorders and ...