Genome|wide association studies in cancer

Genome|wide association studies in cancer—current and future ...

Genome-wide association studies in cancer—current and future ...

Genome-wide association studies (GWAS) have emerged as an important tool for discovering regions of the genome that harbor genetic variants that confer risk ...

Genome-wide association studies of cancer: current insights and ...

Genome-wide association studies (GWAS) uncover the impact of genetic variation on the risk of many common cancers.

Genome-wide association studies in cancer - PubMed

Genome-wide association studies (GWAS) have emerged as an important tool for ... Genome-wide association studies in cancer--current and future directions.

Genome-wide association studies of cancer: current insights and ...

Genome-wide association studies (GWAS) provide an agnostic approach for investigating the genetic basis of complex diseases. In oncology, GWAS of nearly all ...

Genome-wide association studies of cancer: current insights and ...

Genome-wide association studies of nearly all common malignancies have been performed, and over 450 genetic variants associated with increased risks have ...

Genome-wide association studies in common cancers—what have ...

Genome-wide association studies (GWAS) have led to the identification of more than 100 common, low-penetrance loci for cancer.

Genome-wide association studies | Nature Reviews Methods Primers

... current and future applications for GWAS results. Uffelmann et al. describe the key considerations and best practices for conducting genome-wide ...

Genome-wide association studies in cancer—Current and future ...

... Recent genome wide association studies (GWAS), and other case-control studies have revealed that single-nucleotide polymorphisms (SNPs) are the most common ...

Genome-Wide Association Studies of Endometrial Cancer

Future large-scale cross-cancer GWAS meta-analyses are planned to identify genetic risk regions important for carcinogenesis across multiple tissues. Cross- ...

Genome-wide association studies and Mendelian randomization ...

Figure 1 Study design of the early-onset colorectal cancer (EOCRC) genome-wide association study (GWAS) and Mendelian randomization (MR) ...

Genome-wide association studies of cancer: current insights and ...

Key Points The architecture of inherited genetic susceptibility to cancer is defined by a spectrum of predisposition alleles that have differing frequencies ...

Genome- and transcriptome-wide association studies of ... - Cell Press

Significant ancestral differences in risk variant allele frequencies and their association strengths with breast cancer risk were identified. Of ...

Genome-Wide Association Studies of Cancer: Principles and ...

Analysis of genetic variants reviewed here, ongoing studies of structural variation, and future analysis of individual sequence differences ...

Genome-wide and transcriptome-wide association studies of ...

We assessed whether the identified MD phenotype-associated SNPs were also associated with breast cancer risk. Of the 28 lead SNPs, 13 were ...

Genome-wide association studies in cancer - OUCI

Genome-wide association studies in cancer--current and future directions · List of references · Publications that cite this publication.

Genome-Wide Association Studies Fact Sheet

Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease.

After a decade of genome-wide association studies, a new phase of ...

That knowledge can inform the search for new medicines aimed at the molecular causes of illness, bringing us closer to a future of improved ...

Current Landscape of Genome-Wide Association Studies in Acute ...

In oncology, GWAS has been performed in almost every commonly occurring cancer. Despite the increasing number of studies published regarding other malignancies, ...

Common Genetic Variation and Breast Cancer Risk—Past, Present ...

Only a coding variant (D302H) in the caspase 8 gene (CASP8) has consistently shown associations with breast cancer, and ongoing studies have recently identified ...

Genomewide Association Studies and Assessment of the Risk of ...

Genomewide association studies — in which hundreds of thousands of single-nucleotide polymorphisms (SNPs) are tested for association with a ...