Genome|wide identification of transcriptional enhancers during ...

Genome-wide identification of transcriptional enhancers during ...

We hypothesized that mapping sites of transcriptional enhancer activity and associated changes in gene expression across gestation in human ...

Genome-wide identification of transcriptional enhancers during ...

Genome-wide identification of transcriptional enhancers during human placental development and association with function, differentiation, and disease

Genome-Wide Identification of Enhancer Elements in the Placenta

One level of transcriptional control is via enhancer elements in the genome. Enhancers are distal cis-regulatory elements that can impact gene expression ...

Genome-wide identification of enhancers and transcription factors ...

Satellite cells are the myogenic precursor cells in adult skeletal muscle. The objective of this study was to identify enhancers and ...

Transcriptional enhancers: from properties to genome-wide ... - Nature

... DNA interactions in vivo. Figure 3: Genomic methods for predicting enhancers through the detection of transcription factor binding, 'open ...

Genome-wide identification of novel intergenic enhancer-like elements

The molecular mechanisms of transcriptional regulation are poorly understood in Plasmodium falciparum. In addition, most of the genes in ...

Genomic Views of Transcriptional Enhancers

... identity in the genome via the control of lineage-specific transcription patterns. They also enable neural activity-regulated gene induction ...

Transcriptional enhancers: from prediction to functional assessment ...

Genome-wide identification of tissue-specific enhancers in the Ciona tadpole. ... Identifying transcriptional cis-regulatory modules in animal genomes.

Enhancer–promoter specificity in gene transcription - Nature

Advancements in DNA/RNA detection and microscopy techniques have facilitated imaging of EPI. While standard fluorescence in situ ...

Discovering enhancers by mapping chromatin features in primary ...

... genome-wide chromatin profiling has successfully identified enhancers in several pioneering studies. ... transcriptional program, identifying which enhancers ...

Enhanced Identification of Transcriptional Enhancers Provides ...

... TFs primarily regulate gene activity by binding to specific short DNA sequences, termed transcription factor binding sites (TFBSs), or motifs, located in ...

Transcriptional enhancers: from properties to genome-wide ... - OUCI

Tomancak, P. et al. Systematic determination of patterns of gene expression during Drosophila embryogenesis. Genome Biol. 3, research0088-0088.14 (2002). https ...

Genome-wide Identification and Characterization of Enhancers ...

Understanding the tissue-specific gene expression patterns in metazoans is critical for clarifying the molecular mechanisms of transcriptional regulations, ...

Genome-Wide Enhancer Analysis Reveals the Role of AP ... - Frontiers

Master Transcription Factors and Mediator Establish Super-enhancers at Key Cell Identity Genes. Cell 153 (2), 307–319. doi:10.1016/j.cell ...

Identification and Characterization of Enhancers Controlling the ...

Qu, K.A. Ching, et al. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat ...

Enhanced Identification of Transcriptional Enhancers Provides ...

Cap analysis of gene expression (CAGE) identifies transcribed enhancers at exceedingly high nucleotide resolution by detecting enhancer RNAs (eRNAs). Disease- ...

Transcriptional enhancers and their communication with gene ...

... identified genome-wide in silico [327] and in ... transcription factors and mediator establish super-enhancers at key cell identity genes.

Genome‐wide enhancer identification by massively parallel reporter ...

Furthermore, we showed that enhancers differ from promoters in their preference for transcription factors. Although some enhancers are not ...

Transcriptional enhancers: from prediction to functional assessment ...

... gene transcription. Unlike other genomic elements, enhancers are challenging to identify because they function independently of orientation, are often ...

Identification of genomic enhancers through spatial integration of ...

Cellular identity is defined by Gene Regulatory Networks (GRNs), in which transcription factors bind to enhancers and promoters to regulate target gene ...