Genome|wide large|scale multi|trait analysis characterizes global ...

Genome-wide large-scale multi-trait analysis characterizes global ...

Genome-wide association studies (GWAS) have found widespread evidence of pleiotropy, but characterization of global patterns of pleiotropy ...

Genome-wide large-scale multi-trait analysis characterizes global ...

NASA/ADS · Genome-wide large-scale multi-trait analysis characterizes global patterns of pleiotropy and unique trait-specific variants.

(PDF) Genome-wide large-scale multi-trait analysis characterizes ...

PDF | Genome-wide association studies (GWAS) have found widespread evidence of pleiotropy, but characterization of global patterns of pleiotropy remain.

Genome-Wide Large-Scale Multi-Trait Analysis Characterizes ...

Abstract. Genome-wide association studies (GWAS) have found widespread evidence of pleiotropy, but characterization of global patterns of ...

Genome-wide large-scale multi-trait analysis characterizes global ...

Genome-wide large-scale multi-trait analysis characterizes global patterns of pleiotropy and unique trait-specific variants. Author & abstract; Download; 10 ...

Large-scale multitrait genome-wide association analyses identify ...

Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness world-wide. It is often asymptomatic until later stages, causing optic nerve ...

Genome-wide association and multi-trait analyses characterize the ...

Global Biobank Meta-analysis Initiative ... Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr.

Article A large-scale genome-wide cross-trait analysis for the effect ...

Despite lungs being the organ predominately affected, a multi-system involvement of COVID-19 is well-characterized, with extra-pneumatic ...

Genome-wide large-scale multi-trait analysis characterizes global ...

Genome-wide large-scale multi-trait analysis characterizes global patterns of pleiotropy and unique trait-specific variants. https://doi.org/10.1038/s41467 ...

Large scale genome-wide association analyses identify novel ...

Leveraging such correlations, we then performed MTAG with HCM and 3 LV traits including the most correlated trait with HCM from each cluster, namely global ...

Multi-trait analysis reveals risk loci for heart failure and the shared ...

However, the shared genetic etiology underlying these associations remains incompletely understood. Conducting a large-scale multi-trait association study for ...

Sparse matrix factorization of GWAS summary statistics ... - bioRxiv

Genome-Wide Large-Scale Multi-Trait Analysis Characterizes Global. Patterns of Pleiotropy and Unique Trait-Specific Variants. doi:10.1101 ...

Subset-based method for cross-tissue transcriptome-wide ...

27. Qi, G. ∙ Chhetri, S.B. ∙ Ray, D. ... Genome-Wide Large-Scale Multi-Trait Analysis Characterizes Global Patterns of Pleiotropy and Unique Trait-Specific ...

A statistical framework for powerful multi-trait rare variant analysis in ...

Large-scale whole-genome sequencing (WGS) studies have improved our understanding of the contributions of coding and noncoding rare variants to ...

Multi-trait GWAS using imputed high-density genotypes from whole ...

Multi-trait analysis of genome-wide association summary statistics using MTAG. ... Large-scale cognitive GWAS meta-analysis reveals tissue ...

MalteThodberg/awesome-multitrait-gwas - GitHub

2022 fastASSET - Qi - Genome-Wide Large-Scale Multi-Trait Analysis Characterizes Global Patterns of Pleiotropy and Unique Trait-Specific Variants; 2022 - C ...

Multi-trait Analysis of GWAS (MTAG) of Substance Use ... - medRxiv

Johnson, E. C. et al. A large-scale genome-wide association study meta-analysis of cannabis use disorder. Lancet Psychiatry 7, 1032 ...

A multi‐trait analysis of GWAS (MTAG) study

A large-scale genome-wide association study meta-analysis of cannabis use disorder. Lancet Psychiatry. 2020;. 7(12):1032–1045. https://doi.org/10.1016/S2215 ...

Genome-wide analyses of individual differences in ... - PNAS

We present a large-scale well-powered genome-wide association study meta-analysis of individual differences in reading- and language-related skills

Genome-Wide Association Studies (GWAS)

The method involves surveying the genomes of many people, looking for genomic variants that occur more frequently in those with a specific disease or trait ...