Genome assemblies
A genome assembly is a computational representation of a genome sequence. Because we are not able to sequence along the complete length of a chromosome, each ...
Genome Assembly - an overview | ScienceDirect Topics
A genome assembly is simply the sequence produced after all of the chromosomes of a target species have been fragmented (a large number of short/long DNA ...
The human genome assembly was produced as part of the Human Genome Project (HGP). The previous assembly (NCBI36) was the last one produced by ...
Towards complete and error-free genome assemblies of all ... - Nature
High-quality and complete reference genome assemblies are fundamental for the application of genomics to biology, disease, and biodiversity ...
An Overview of Genome Assembly
Genome assembly represents the process of putting a large number of short DNA sequences back together to recreate the original chromosomes from which the DNA ...
In bioinformatics, sequence assembly refers to aligning and merging fragments from a longer DNA sequence in order to reconstruct the original sequence.
A beginner's guide to assembling a draft genome and analyzing ...
We present a step-by-step analysis of long-read DNA sequencing, which includes the software installation, genome assembly, quality assessment, SV calling, and ...
De novo genome assembly: what every biologist should know - Nature
As genome assembly programs stitch together an organism's chromosomes from fragmented reads of DNA, they perform some of the most complex ...
The NCBI Genome Assembly Data Model
NCBI provides stable accessions and data tracking for genome assemblies. It stores the names and identifiers for the sequences in each genome assembly.
QUAST: quality assessment tool for genome assemblies
A quality assessment tool for evaluating and comparing genome assemblies. This tool improves on leading assembly comparison software with new ideas and quality ...
BlobToolKit – Interactive Quality Assessment of Genome Assemblies
BlobToolKit can be used to process assembly, read and analysis files for fully reproducible interactive exploration in the browser-based Viewer. BlobToolKit can ...
The changing face of genome assemblies: Guidance on achieving ...
Here, we highlight advances in technology that have raised the bar for genome assembly and provide guidance on standards to achieve exceptional quality ...
Mind the gap; seven reasons to close fragmented genome assemblies
Here we discuss a number of important reasons to produce gapless, finished, genome assemblies to help answer important biological questions.
GenomeQC: a quality assessment tool for genome assemblies and ...
An easy-to-use and interactive web framework that integrates various quantitative measures to characterize genome assemblies and annotations.
assessing the quality of genome assemblies with the 3 Cs - PacBio
Assemblies should be evaluated in the three key dimensions: contiguity, completeness, and correctness.
What is a genome assembly? - NLM Support Center
An assembly can be defined as a collection of sequence records that represent a genome. More than one assembly may be available at NCBI for an individual ...
Introduction to de novo genome assembly for Illumina reads
In this protocol we discuss and outline the process of de novo assembly for small to medium sized genomes.
Fundamentals of Genome Assembly - YouTube
This is the sixth lecture in the Informatics on High-Throughput Sequencing Data 2017 workshop hosted by the Canadian Bioinformatics ...
Genome Assembly Service - BV-BRC
A tutorial showing how to submit reads of various types for assembly and selecting parameters for the assembly algorithm.
Submitting Genome Assemblies of Individuals or Cultured Isolates
Submitting Genome Assemblies of Individuals or Cultured Isolates · Introduction · Stage 1: Pre-Register Study And Sample · Stage 2: Prepare The Files · Stage 3 ...