Genotype Imputation for Latinos Using the HapMap and ...

Genotype Imputation for Latinos Using the HapMap and 1000 ...

Our results show that the 1000 Genomes Project AMR + CEU + YRI reference panel provides the highest imputation accuracy for Latinos, and that also including ...

Genotype Imputation for Latinos Using the HapMap and 1000 ...

Multiple GWAS and meta-analyses are targeting Latinos, the most populous, and fastest growing minority group in the US. However, genotype ...

(PDF) Genotype Imputation for Latinos Using the HapMap and 1000 ...

Multiple GWAS and meta-analyses are targeting Latinos, the most populous, and fastest growing minority group in the US. However, genotype ...

https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene ...

... genotype imputation in Latinos using public imputation ... We present the first extensive evaluation of genotyping imputation for Latinos using the HapMap and ...

Improved imputation accuracy in Hispanic/Latino populations with ...

Our assessments included calculating the correlation between imputed and observed allelic dosage in a subset of samples genotyped on a supplemental array. We ...

Genotype imputation accuracy by chromosome. Genotype ...

... Latinos Using the HapMap and 1000 Genomes Project Reference Panels | Genotype imputation ... genotyped, using a specialized imputation protocol for Latino ...

Comprehensive Assessment of Genotype Imputation Performance

Imputation was performed on SNP data of 4× and 7× from 1KG_ALL using IMPUTE2 because of its better performance on 10 individuals. The SNP ...

Comparing performance of modern genotype imputation methods in ...

The original POPRES data was based on the Genomic assembly Affymetrix release 25 NSP25 and STY25 with dbSNP Build 126, released on May 2006.

Genotype Imputation for Admixed Populations - Wiley Online Library

That imputation performance for Hispanics is comparable with that for African Americans is expected due to on average less African ancestry ( ...

Evaluation of the imputation performance of the program IMPUTE in ...

The sample from Mexico City comprised 1,310 individuals genotyped with the Affymetrix 5.0 array. We randomly masked 5% of the markers directly ...

A Genome-Wide Association Study of Central Corneal Thickness in ...

... with genotype imputation based on the 1000 Genome ... 36. Gao X Haritunians T Marjoram P Genotype imputation for Latinos using the HapMap and 1000 Genomes Project ...

A broad overview of genotype imputation: Standard guidelines ...

The possibility to predict haplotypes and, therefore, alleles of ungenotyped variant loci arose from the fundamental concept in genetics that ...

Genotype Imputation with Thousands of Genomes - Oxford Academic

Using data from HapMap 3, we show that our framework produces accurate results in a wide range of human populations. We also use data from the ...

[PDF] Haplotype variation and genotype imputation in African ...

Front. Gene. 2012. TLDR. Evaluated the accuracy of genotype imputation in Latinos using simulation studies, the ...

Amerindian-specific regions under positive selection harbour new ...

We performed GWAS for high TGs in Mexicans using only the CPAS SNPs as the input. HDLC, TC and BMI were analysed as continuous traits instead to ...

HapMap 3 - Wellcome Sanger Institute

Linkage disequilibrium analysis; SNP Tagging; Imputation efficiency; Genomic locations of human CNVs; Genotypes for CNVs; Population genetic properties of CNVs ...

Design and coverage of high throughput genotyping arrays ...

Simulations show that imputation is potentially the most beneficial for rare variants, which are harder to tag with a single marker [13]. Several papers that ...

HapMap 3 - Broad Institute

... HapMap 3" samples). This release contains the following data: SNP genotype data generated from 1115 samples, collected using two platforms: the Illumina ...

Assessment of Genotype Imputation Performance Using 1000 ...

Overall, imputation has typically relied on HapMap reference haplotype panels from Africans (YRI), European Americans (CEU), and Asians (CHB/JPT). The 1000 ...

Genotype Imputation Performance of Three Reference Panels Using ...

The 1000G, HRC and CAAPA participants of African ancestry provided high performance and accuracy for imputation of African American admixed ...