Genotype imputation for Han Chinese population using Haplotype ...

Genotype imputation is now routinely performed in genomic analysis. Reference panel size, that is, the number of haplotypes in the reference panel, ...

Our study showcases the limitations of HRC for Han Chinese populations, strongly suggesting the necessity of building population-specific reference panels.

Genotype imputation and reference panel: a systematic evaluation ...

However, for the Han Chinese population, the accuracy of all imputed variants reached the highest when reference panel contained a fraction of an extra diverse ...

Imputation - 汉族基因组数据库

Genotype imputation, or simply imputation in the context of our database, is to estimate the unobserved genotypes in the given dataset. Our imputation service ...

A high-resolution haplotype-resolved Reference panel constructed ...

It is particularly important to construct highly accurate haplotype reference panel for genotype imputation. In this study, we used 10 000 ...

The ChinaMAP reference panel for the accurate genotype ... - Nature

The limited Chinese samples restrict the imputation quality with current reference panels in Chinese population studies. Additionally, the ...

Genotype imputation for Han Chinese population using Haplotype ...

Genotype imputation for Han Chinese population using Haplotype Reference Consortium as reference · Yuan Lin · Lu Liu · Sen Yang · Yun Li · Dongxin Lin · Xuejun Zhang ...

Genotype Imputation and Reference Panel: A Systematic Evaluation

But for Han Chinese population, the accuracy of all imputed variants reached the highest when reference panel contained a fraction of extra ...

Genotype imputation and reference panel: A systematic evaluation ...

Here, 622 imputations were conducted with 394 customized reference panels for Han Chinese and European populations.

A diverse ancestrally-matched reference panel increases genotype ...

We found that imputation using the TOPMed panel yielded the largest number of variants (~ 271 million). Despite being the smallest in size, GenomeAsia 100 K ...

NyuWa Genome resource: A deep whole-genome sequencing ...

For the Han Chinese population, imputation with NyuWa reduced the error rates by 38.1%, 50.8%, and 30.4% compared with 1KGP3, HRC.r1.1, and ...

Genotype imputation and reference panel: a systematic evaluation ...

Here, 622 imputations were conducted with 394 customized reference panels for Han Chinese and European populations. Besides validating the fact that ...

Genotype imputation for Han Chinese population using Haplotype ...

Abstract Genotype imputation is now routinely performed in genomic analysis. Reference panel size, that is, the number of haplotypes in the reference ...

Evaluation of a SNP-STR haplotype panel for forensic genotype ...

To further study the performance of genotype imputation in forensic fields, we collected STR, microhaplotype (MH) and SNP array genotypes from Chinese Han ...

Evaluation of a SNP-STR haplotype panel for forensic genotype ...

... genotype imputation using a dataset with ... Chinese Han population and its application in estimating the number of contributors in DNA mixtures.

Genotype imputation accuracy and the quality metrics of the minor ...

We imputed genotypes of East Asian (180k Japanese) subjects using the Trans-Omics for Precision Medicine reference panel and found that the ...

NARD: whole-genome reference panel of 1779 Northeast Asians ...

... genetic research in these populations ... Genotype imputation for Han Chinese population using Haplotype Reference Consortium as reference.

Overcoming the challenges of imputation of rare variants in a ...

Figure 1 Workflow for genotype imputation in a Taiwanese cohort using ... Genotype imputation for Han Chinese population using Haplotype Reference Consortium as ...

Validation of genotype imputation in Southeast Asian populations ...

The imputed outcomes were verified with the removed SNPs. We compared imputation references from Chinese and Japanese haplotypes from the ...

Genotype imputation for Han Chinese population using Haplotype ...

Genotype imputation for Han Chinese population using Haplotype Reference Consortium as reference. Hum. Genet. Pub Date : 2018-06-02. DOI : 10.1007/s00439-018 ...