Global management of brain metastasis from renal cell carcinoma

During the last decade, major improvements have been made in the treatment of renal cell carcinoma (RCC) with the development and use of ...

Treatment is based on surgery, radiotherapy, and systemic therapy. Recent progress has been made in all these areas. Combination of these treatments seems to ...

Management of brain metastases from renal cell carcinoma - PMC

The aims of treating brain metastases can be the relief of neurological symptoms and tumor control. Surgery, radiotherapy, and/or systemic medical therapies are ...

Global management of brain metastasis from renal cell carcinoma

BM: Brain metastases, Ds-GPA: Diagnosis-specific graded prognostic assessment, IMDC: International metastatic renal cell carcinoma database ...

First-Line Systemic Immunotherapy, Local Treatments Best for Renal ...

Patients with brain metastases from renal cell carcinoma may benefit from systemic combination immunotherapy as well as brain-directed local ...

An interdisciplinary consensus on the management of brain ...

Brain metastases are a challenging manifestation of renal cell carcinoma. We have a limited understanding of brain metastasis tumor and immune ...

Outcomes of Patients with Brain Metastases from Renal Cell ...

Patients receiving intensive therapies such as immuno-oncology-based combination therapy, stereotactic radiotherapy, or neurosurgery had ...

Brain Metastases From Renal Cell Carcinoma Treated With First-line ...

This research shows that brain metastasis at the start of systemic therapy affects about 7.9% of patients with metastatic RCC who start first-line treatment.

Incidence of brain metastases in renal cell carcinoma treated with ...

Conclusions: In this subpopulation, sorafenib may reduce the occurrence of brain metastases. Antiangiogenic therapy, such as sorafenib, could be an effective ...

Brain Metastasis and Renal Cell Carcinoma: Prognostic Scores ...

Brain metastases occur in 10% of metastatic RCC patients (6). Local treatment options such as surgery or radiotherapy are considered the standard of care to ...

Outcomes of patients with brain metastases from renal cell ...

Conclusions: Patients with brain metastases receiving IO-based combination therapy may have longer OS than those receiving anti-VEGF monotherapy ...

Clinical outcomes in patients with metastatic renal cell carcinoma ...

These data are consistent with the well-established practice of local CNS-directed therapy with either surgical resection of radiotherapy followed by systemic ...

Clinical Activity and Safety of Cabozantinib for Brain Metastases in ...

Importance Patients with brain metastases from renal cell carcinoma (RCC) have been underrepresented in clinical trials, and effective systemic ...

Current Multimodality Treatments against Brain Metastases from ...

In patients with renal cell carcinoma, brain metastasis is generally one of the poor prognostic factors. However, the recent introduction of molecular ...

Brain Metastases in Patients with Kidney Cancer May Have Immune ...

In patients with renal cell carcinoma, brain metastases had distinct gene expression programs and lower antitumor immune cell infiltration ...

Radiation necrosis in renal cell carcinoma brain metastases treated ...

The concurrent administration of immune checkpoint inhibitors and stereotactic radiosurgery in patients with renal cell carcinoma brain ...

Prognostic Factors and Current Treatment Strategies for Renal Cell ...

The well-recognized prognostic factors for brain metastatic renal cell carcinoma (BMRCC) are Karnofsky Performance Status (KPS), the number of brain metastasis ...

Outcomes in Brain Metastatic Renal Cell Carcinoma Treated with ...

Stereotactic radiosurgery (SRS) and fractionated stereotactic radiation therapy (FSRT) are effective treatment modalities for the local control of brain ...

Advanced Renal Cell Carcinoma and Brain Metastases - OncLive

Eric Jonasch, MD: Because we can't guarantee that these therapies are effective, we've used radiation therapy, stereotactic radiosurgery, to the ...

Targeted drug shows activity against brain metastases in kidney ...

Cancer drugs have shown little benefit in patients with kidney cancer metastatic to the brain · A study of cabozantinib, a drug that hits ...