HSFs drive transcription of distinct genes and enhancers during ...

HSFs drive transcription of distinct genes and enhancers ... - PubMed

We show that pause-release of RNA polymerase II (Pol II) is a universal mechanism regulating gene transcription in stressed cells, while ...

We show that HSFs function as multi-stress-responsive factors that activate distinct genes and enhancers when encountering changes in temperature and redox ...

HSFs drive transcription of distinct genes and enhancers during ...

Under oxidative stress, HSF1 localizes to a unique set of promoters and enhancers to trans-activate oxidative stress-specific genes. Taken ...

HSFs drive transcription of distinct genes and enhancers during ...

Dive into the research topics of 'HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock'. Together ...

HSFs drive transcription of distinct genes and enhancers during ...

HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock · Abstract · List of references · Publications that cite this ...

HSFs drive transcription of distinct genes and enhancers during ...

Reprogramming of transcription is critical for the survival under cellular stress. Heat shock has provided an excellent model to investigate nascent ...

Heat shock transcription factors demonstrate a distinct mode ... - NCBI

A large screen of TF localization during mitosis by live-cell imaging reported varying degrees of DNA-TF interactions, from strongly enriched on mitotic DNA, ...

The Heat Shock Factor Code: specifying a diversity of transcriptional ...

HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock. Nucleic Acids Res, 50 (2022), pp. 6102-6115 ...

Transcriptional reprogramming at the intersection of the heat shock ...

The dramatic rewiring of gene and enhancer networks is driven by key transcription factors, including heat shock factors (HSFs), that together ...

Transcriptional responses of cancer cells to heat shock-inducing ...

HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock. Nucl. Acids Res. 50, 6102–6115 (2022) ...

Transcriptional response to stress is pre-wired by promoter ... - Nature

Programs of gene expression are executed by a battery of transcription factors that coordinate divergent transcription from a pair of ...

HSF2 cooperates with HSF1 to drive a transcriptional program ...

Regulation of these genes by HSF2 is critical for the cellular response to cancer-associated stressors in a manner distinct from its dispensable ...

Interplay between mammalian heat shock factors 1 and 2 in ...

The heat-shock factors (HSFs) belong to an evolutionary conserved family of transcription factors that were discovered already over 30 years ...

Comparison of the functional domains of human HSF1 and HSF2 ...

... HSFs to access unique sites depending on the type of stress. ... HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock.

Quantifying RNA synthesis at rate-limiting steps of transcription ...

Publications that cite this publication · HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock · CCG-1423-derived ...

HSFs drive transcription of distinct genes and enhancers during ...

HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock · FNT Common · Biokemia ja solubiologia.

Enhancer selectivity across cell types delineates three functionally ...

We observe two well-known gene regulation patterns controlled by enhancer clusters, which regulate the same gene either in a limited number of ...

The Role of Heat Shock Transcription Factor 1 in the Genome-wide ...

These results provide evidence that HSF1 does not regulate the induction of every transcript that accumulates after heat shock, and our results ...

HSF4 is required for normal cell growth and differentiation during ...

The heat shock transcription factor (HSF) family consists of three members in mammals and regulates expression of heat shock genes via a heat shock element.

Developmental and housekeeping transcriptional programs display ...

Although enhancers have been extensively studied in isolation, a substantial number of genes have more than one simultaneously active enhancer, ...