Hepatitis B core|based virus|like particles

Hepatitis B core-based virus-like particles: A platform for vaccine ...

This review investigates the application of plant-based HBc VLP as a platform for vaccine production.

Hepatitis B core-based virus-like particles: A platform for vaccine ...

Virus-like particles (VLPs) are a class of structures formed by the self-assembly of viral capsid protein subunits and contain no infective ...

Covalent protein display on Hepatitis B core-like particles in plants ...

Unidirectional display of antigens avoiding steric hindrance can be achieved using the SpyTag/SpyCatcher technology. This system is based on the ...

Chimeric Hepatitis B core virus-like particles harboring SARS-CoV2 ...

Virus-like particles are an interesting vector platform for vaccine development. Particularly, Hepatitis B virus core antigen has been used ...

Synthesis and Assembly of Hepatitis B Virus-Like Particles in a ...

Using a recently developed Pichia pastoris-based CFPS system, we have demonstrated the production of the model Hepatitis B core antigen VLP as a proof-of- ...

Introducing adjuvant-loaded particulate hepatitis B core antigen as ...

therapeutic hepatitis B vaccine. TLR. Toll-like receptor. Introduction. The first virus-like particle used as a vaccine carrier was based on the HBV capsid.

Modular Hepatitis B Virus-like Particle Platform for Biosensing and ...

We aim to create a robust and highly modular method to produce smart HBV-based nanodevices by using the SpyCatcher/SpyTag system.

A hepatitis B virus core antigen‐based virus‐like particle vaccine ...

The hepatitis B virus core antigen (HBcAg) tolerates insertion of foreign epitopes and maintains its ability to self-assemble into ...

Hepatitis B core particles as a universal display model

Supermolecular structures built in a symmetric manner from hundreds of proteins of one or more types, often called VLPs (virus-like particles), could serve as ...

Preparation by alkaline treatment and detailed characterisation of ...

Hepatitis B virus (HBV) core (HBc) virus-like particles (VLPs) are ... A universal virus-like particle-based vaccine for human ...

Inherent symmetry and flexibility in hepatitis B virus subviral particles

The virion is composed of a 36-nm-diameter icosahedral nucleocapsid core containing the DNA genome enveloped by a lipid membrane with embedded ...

Computational Design of a Novel VLP-Based Vaccine for Hepatitis B ...

Molecular dynamics (MD) analysis of hepatitis B core antigen (HBcAg) and the designed virus-like particle (VLP)-based vaccine during 100-ns ...

The true story and advantages of the famous Hepatitis B virus core ...

The most important of these is the HBV core protein p21, or HBc. It can self-assemble by forming viral HBc particles, but also plays a crucial ...

Absolute Quantification of Hepatitis B Core Antigen (HBcAg) Virus ...

We investigated a silica spin column (SC)-based extraction procedure, including proteinase K lysis and silica chromatography, for the absolute quantification ...

Hepatitis B core–based virus–like particles to present heterologous ...

Hepatitis B core–based virus–like particles to present heterologous epitopes · Abstract · HBV surface antigen: the viral surface glycoprotein ...

Tandem Fusion of Hepatitis B Core Antigen Allows Assembly of ...

The core protein of the hepatitis B virus, HBcAg, assembles into highly immunogenic virus-like particles (HBc VLPs) when expressed in a variety of ...

Enhanced stability of a chimeric hepatitis B core antigen virus-like ...

In summary, we developed a molecular simulated model for the hexahistidine-peptide-dependent particle stabilizing effect based on cryo-electron ...

Three-Dimensional Structure of Hepatitis B Virus Core Particles ...

In human hepatitis B virus (HBV), the core antigen (HBcAg) particle packages the pregenomic RNA (Junker-Niep- mann et al., 1990) and forms an active complex ...

Custom Hepatitis B Virus (HBV) Virus-Like Particle (VLP) Production ...

VLPs are widely known as empty shells of the virus without genomic materials. They share the same virion structural properties while lacking the ability to ...

Hepatitis B core–based virus–like particles to present heterologous ...

Since the first effort to recombinantly express the hepatitis B core protein (HBc) in bacteria, the remarkable virion-like structure has fuelled interest in ...