Events2Join

High|Throughput Quantitative Assay Technologies for Accelerating ...


High-Throughput Quantitative Assay Technologies for Accelerating ...

A number of techniques and technologies have emerged that have helped to accelerate targeted protein degradation drug discovery efforts.

(PDF) High-Throughput Quantitative Assay Technologies for ...

Traditional approaches for quantifying protein level changes in cells, such as Western blots, are typically low throughput with limited quantification, making ...

High-Throughput Quantitative Assay Technologies for Accelerating ...

In the last decade, a number of techniques and technologies have emerged that have helped to accelerate targeted protein degradation drug discovery efforts, ...

A High-Throughput Solution To Accelerate Drug Discovery

Minimize sample handling, reduce carryover and greatly diminish the effects of suppressive buffers · Achieve unparalleled standards of ...

Tech Focus: How is HTS accelerating early-stage drug discovery?

High-throughput screening (HTS) utilises robotics and automation to allow testing of large numbers of chemical and/or biological compounds ...

Accelerating Drug Discovery with High-Throughput Technologies

High-throughput screening has become much more than just massive-scale binding assays, embracing technologies from fields as diverse as high ...

Adaptation of High-Throughput Screening in Drug Discovery ...

HTS assays are used for screening of different types of libraries, including combinatorial chemistry, genomics, protein, and peptide libraries. The main goal of ...

Press Releases - Bio-Techne

The enhanced quantitation, reproducibility and throughput Leo now provides makes it possible for scientists to adopt western-based readouts in ...

Accelerating Discovery and Development with Advances in High ...

Many HTS technologies for Hit-ID · Numerous advantages for process development · Recent assay developments · Automation and miniaturization ...

Accelerating biologics discovery and cell development - News-Medical

A) A quantitative competition FRET assay ... That's why our technologies boost throughput and assay sensitivity across a range of applications.

Quantitative high-throughput screening: A titration-based approach ...

We have developed a paradigm, quantitative HTS (qHTS), tested with the enzyme pyruvate kinase, to generate concentration–response curves for >60,000 compounds ...

In vivo quantitative high-throughput screening for drug discovery ...

Quantitative high-throughput screening (qHTS) pharmacologically evaluates chemical libraries for therapeutic uses, toxicological risk and, increasingly, ...

SAGE Publishing - Altmetric

High-Throughput Quantitative Assay Technologies for Accelerating the Discovery and Optimization of Targeted Protein Degradation Therapeutics.

A direct high-throughput protein quantification strategy facilitates ...

Although various assay technologies, including in-cell western, ELISA, AlphaLISA, and luciferase-reporter systems, have been developed to increase accuracy and ...

A protocol for high-throughput screening for immunomodulatory ...

High-throughput screening is a powerful platform that can rapidly provide valuable cytotoxic, immunological, and phenotypical information for ...

Accelerating the Development of Novel Molecular Imaging Probes

HTS assays with model organisms of various types are rapidly gaining favor for small-molecule discovery because they represent a bridge between potentially ...

High-Throughput Screening Methods for Drug Discovery

In this article, we will discuss how the use of different high-throughput screening (HTS) methods can help to accelerate the drug discovery process.

Cell Painting-based bioactivity prediction boosts high-throughput ...

A comprehensive analysis shows that Cell Painting-based bioactivity prediction is robust across assay types, technologies, and target classes.

High-throughput cytometry for faster, simpler cell analysis

The life science group Sartorius has released its second edition of the “High-Throughput Screening (HTS) by Cytometry” handbook, ...

High-Throughput Screening for Swift Compound Analysis

High-throughput automation solutions by SCIEX, such as the integrated Echo MS system and the LeadScape Analyze software, provide rapid, ...