High Interstitial Fluid Pressure Is Associated with Low Tumour ...

Dense vascularisation was only present at the margins of the tumours. The existing blood vessels were irregular and were denoted as immature ( ...

High interstitial fluid pressure is associated with low tumour ...

A higher interstitial fluid pressure of about 12 mbar was measured in the HT29 primary tumour via wick-in-needle technique which could explain the limited ...

Interstitial fluid pressure as an emerging biomarker in solid tumors

The physical microenvironment of cancer is characterized by elevated stiffness and tissue pressure, the main component of which is the interstitial fluid ...

High Interstitial Fluid Pressure Is Associated with Tumor-Line ... - PLOS

High IFP has been associated with low radiocurability and high metastatic frequency in human melanoma xenografts and with poor survival after radiation therapy ...

Interstitial Fluid Pressure and Associated Lymph Node Metastasis ...

Tumor tissues develop interstitial hypertension because they show high resistance to blood flow, low resistance to transcapillary fluid flow ...

Interstitial fluid pressure, vascularity and metastasis in ectopic ...

High tumour interstitial fluid pressure (IFP) has been adversely linked to poor drug uptake in patients, and to treatment response following radiotherapy in ...

Interstitial fluid pressure regulates collective invasion in engineered ...

Many solid tumors exhibit elevated interstitial fluid pressure (IFP). This elevated pressure within the core of the tumor results in outward flow of ...

High interstitial fluid pressure promotes tumor cell proliferation and ...

The elevated IFP in tumors is responsible, at least in part, for the poor blood supply, inadequate delivery of therapeutic agents to solid ...

Tumor Interstitial Fluid Pressure—A Link between Tumor Hypoxia ...

High microvascular density (MVD) in the primary tumor has been shown to be associated with increased incidence of lymph node metastases and poor clinical ...

High interstitial fluid pressure — an obstacle in cancer therapy

Lowering the tumour IFP with specific signal-transduction antagonists might be a useful approach to improving anticancer drug efficacy.

The peptide AF-16 decreases high interstitial fluid pressure in solid ...

High interstitial fluid pressure (IFP) is a characteristic feature of most solid, malignant tumors [Citation1]. The increased IFP disturbs the blood flow and ...

Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer

... associated with low immune response and poor prognosis in pancreatic cancer ... High interstitial fluid pressure - an obstacle in cancer therapy.

Measurement of Tumor Pressure and Strategies of Imaging Tumor ...

Most strikingly, tumor-associated abundant ECM increases the interstitial fluid pressure (IFP) compared with that of a normal tissue. High-IFP ...

Coevolution of Solid Stress and Interstitial Fluid Pressure in Tumors ...

The mechanical microenvironment of solid tumors is characterized by both fluid- and solid-phase stresses. Fluid-phase stresses include the vascular and ...

Therapeutic implications of tumor interstitial fluid pressure in ...

In brain tumors, the mechanisms responsible for increased tumor IFP are not fully understood, but increased vascular permeability, coupled with high resistance ...

Interstitial Fluid Pressure - IFP - Steele Labs

Finally, decreased fluid convection into the peri-tumor tissue would decrease peri-tumor edema associated with brain tumors and ascites accumulation in the ...

Interstitial fluid pressure as an emerging biomarker in solid tumors

This phenomenon is typically characterized by a noticeably high interstitial fluid pressure in tumors (IFP; in the range of 10-100 mmHg) compared to normal ...

DW-MRI in assessment of the hypoxic fraction, interstitial fluid ...

Cancer patients with primary tumors showing extensive hypoxia and highly elevated interstitial fluid pressure (IFP) have poor prognosis. The ...

Interstitial fluid pressure in tumors: therapeutic barrier and biomarker ...

Reductions in interstitial fluid pressure due to anti-angiogenic treatment have been associated with improved therapeutic outcome in preclinical studies ...

Interstitial Fluid Pressure in Tumors: Therapeutic Barrier and ...

High interstitial fluid pressure is an independent predictor of disease recurrence in cervical cancer patients treated with radiotherapy, has ...