- High interstitial fluid pressure — an obstacle in cancer therapy🔍
- High interstitial fluid pressure🔍
- Interstitial fluid pressure as an emerging biomarker in solid tumors🔍
- High interstitial fluid pressure|an obstacle in cancer therapy.🔍
- High Interstitial Fluid Pressure Is Associated with Low Tumour ...🔍
- Interstitial fluid pressure🔍
- Interstitial fluid pressure as an obstacle in treatment of solid tumors🔍
- Therapeutic implications of tumor interstitial fluid pressure in ...🔍
High interstitial fluid pressure — an obstacle in cancer therapy
High interstitial fluid pressure — an obstacle in cancer therapy - Nature
Many solid tumours show an increased interstitial fluid pressure (IFP), which forms a barrier to transcapillary transport. This barrier is an obstacle in ...
High interstitial fluid pressure - an obstacle in cancer therapy
Many solid tumours show an increased interstitial fluid pressure (IFP), which forms a barrier to transcapillary transport. This barrier is an obstacle in ...
High interstitial fluid pressure — an obstacle in cancer therapy
Many solid tumours show an increased interstitial fluid pressure (IFP), which forms a barrier to transcapillary transport. This barrier is an obstacle in ...
High interstitial fluid pressure — an obstacle in cancer therapy
Lowering the tumour IFP with specific signal-transduction antagonists might be a useful approach to improving anticancer drug efficacy.
Interstitial fluid pressure as an emerging biomarker in solid tumors
Elevated IFP is an established negative predictive and prognostic parameter, directly affecting malignant behavior and therapy response. As such, measurement of ...
(PDF) Heldin CH, Rubin K, Pietras K, Ostman AHigh interstitial fluid ...
Many solid tumours show an increased interstitial fluid pressure (IFP), which forms a barrier to transcapillary transport. This barrier is an obstacle in ...
High interstitial fluid pressure-an obstacle in cancer therapy.
Document Type: Article ; Subject Terms: *TUMORS *INTERPHOTORECEPTOR matrix *EXTRACELLULAR fluid *DRUG efficacy *ENZYME inhibitors *ANTINEOPLASTIC antibiotics.
High Interstitial Fluid Pressure Is Associated with Low Tumour ...
Although an antibody against EpCAM has successfully been used as an adjuvant therapy in colon cancer, this therapy has never gained wide-spread ...
Interstitial fluid pressure, vascularity and metastasis in ectopic ...
High tumour interstitial fluid pressure (IFP) has been adversely linked to poor drug uptake in patients, and to treatment response following radiotherapy in ...
Interstitial fluid pressure as an obstacle in treatment of solid tumors
normal tissue, the extravasation of the drug molecules from vessels into the tumor interstitium is reduced due to elevated interstitial fluid pressure (IFP).
Therapeutic implications of tumor interstitial fluid pressure in ...
In brain tumors, the mechanisms responsible for increased tumor IFP are not fully understood, but increased vascular permeability, coupled with high resistance ...
Intratumor Heterogeneity in Interstitial Fluid Pressure in Cervical and ...
IFP is generally higher in intramuscular than in subcutaneous tumors, possibly because the resistance to interstitial fluid flow from the tumor tissue into the ...
High interstitial fluid pressure — an obstacle in cancer therapy - OUCI
Boucher, Y. et al. Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse.
Interstitial fluid pressure regulates collective invasion in engineered ...
Importantly, our results suggest that elevated IFP in vivo, which manifests as interstitial hypertension, also affects cancer cell behavior. Interstitial ...
Overview of Methods for Overcoming Hindrance to Drug ... - Frontiers
Increased leakiness combined with increased inflammatory byproducts accumulates fluid within the tumor mass (tumor interstitial fluid), ultimately creating an ...
Interstitial Fluid Pressure as a Prognostic Factor in Cervical Cancer ...
Pre–radiation therapy interstitial fluid pressure was significantly higher in adenocarcinomas than squamous cell carcinomas (P = 0.028). Significant reduction ...
Interstitial Fluid Pressure and Associated Lymph Node Metastasis ...
Malignant solid tumors generally have a higher interstitial fluid pressure (IFP) than normal tissues (1–3). Tumor tissues develop interstitial ...
High interstitial fluid pressure -- an obstacle in cancer therapy. - Gale
In 1987, Jain hypothesized that the osmotic pressure in tumours must be high and that the high tumour interstitial fluid pressure (IFP) is a barrier for ...
The peptide AF-16 decreases high interstitial fluid pressure in solid ...
The high IFP causes a “compartment syndrome” preventing access of oxygen and cancer chemotherapy. A lowering of the tumor IFP is likely to facilitate the ...
Interstitial Fluid Pressure in Tumors: Therapeutic Barrier and ...
... 1 The efficacy of systemic cancer therapies is limited by poor drug penetration in tumor tissue. 2 The major obstacle for tissue penetration ...