- How does the TOM complex mediate insertion of precursor proteins ...🔍
- Atomic structure of human TOM core complex🔍
- Translocase of the Outer Membrane🔍
- Mechanisms and pathways of mitochondrial outer membrane ...🔍
- Biogenesis of the mitochondrial TOM complex🔍
- Lateral release of proteins from the TOM complex into the outer ...🔍
- Targeting and Insertion of Membrane Proteins in Mitochondria🔍
- The Preprotein Translocation Channel of the Outer Membrane of ...🔍
How does the TOM complex mediate insertion of precursor proteins ...
How does the TOM complex mediate insertion of precursor proteins ...
A multisubunit translocase of the outer mitochondrial membrane (TOM complex) mediates both the import of mitochondrial precursor proteins into the internal ...
Atomic structure of human TOM core complex | Cell Discovery - Nature
The translocase of the outer mitochondrial membrane (TOM) complex is the main entry gate for mitochondrial precursor proteins synthesized on ...
Translocase of the Outer Membrane - an overview - ScienceDirect.com
In mitochondria, the β-barrel precursors (line with arrows), after passing the TOM complex, are inserted into the outer membrane from the inner surface in a ...
Mechanisms and pathways of mitochondrial outer membrane ...
2. Protein entry into mitochondria. The TOM complex imports most of the mitochondrial precursor proteins into mitochondria. It consists of seven subunits. The ...
Biogenesis of the mitochondrial TOM complex - Cell Press
The translocase at the outer membrane of mitochondria (TOM complex) mediates the initial steps of the import of preproteins into the organelle, which are ...
Lateral release of proteins from the TOM complex into the outer ...
The TOM complex of the outer membrane of mitochondria is the entry gate for the vast majority of precursor proteins that are imported into the mitochondria.
Targeting and Insertion of Membrane Proteins in Mitochondria
Beta-barrel proteins of the outer membrane are first translocated into the IMS via the TOM complex. The small TIM chaperones then transfer β-barrel precursors ...
The Preprotein Translocation Channel of the Outer Membrane of ...
After reconstitution into lipid vesicles, the purified TOM complex is capable of mediating the insertion of outer membrane proteins, the import of intermembrane ...
How does the TOM complex mediate insertion of precursor proteins ...
How does the TOM complex mediate insertion of precursor proteins into the mitochondrial outer membrane? (English). 1 reference.
Mitochondrial targeting of tBid/Bax: a role for the TOM complex?
They are bound by IMS chaperones that deliver the proteins to the SAM machinery, which mediates the insertion of the β-barrel proteins into the ...
Mim1, a protein required for the assembly of the TOM complex of ...
The translocase of the outer mitochondrial membrane (TOM complex) is the general entry site for newly synthesized proteins into mitochondria.
Functions of the Small Proteins in the TOM Complex of Neurospora ...
The TOM complex (translocase of the outer mitochondrial membrane) is responsible for the initial recognition of virtually all mitochondrial precursors ...
Targeting and Insertion of Membrane Proteins in Mitochondria
Unfolded precursors are then trafficked to the mitochondrial outer membrane where they come into contact with the TOM complex via specific ...
Transport of proteins across or into the mitochondrial outer membrane
In order to handle loosely folded or unfolded precursor polypeptides, those translocators cooperate with chaperones in the cytosol and intermembrane space, and ...
Structural snapshot of the mitochondrial protein import gate - Araiso
The translocase of the outer mitochondrial membrane (TOM) complex is the main entry gate for most mitochondrial proteins. The TOM complex is ...
Alternative function for the mitochondrial SAM complex in ...
The channel-forming Tom40 is a β-barrel protein, whereas all Tom receptors and small Tom proteins are membrane anchored by a transmembrane α- ...
Towards a molecular mechanism underlying mitochondrial protein ...
For the majority, the first port of call is the translocase of the outer membrane (TOM complex), followed by a procession of alternative ...
Peeping at TOMs—Diverse Entry Gates to Mitochondria Provide ...
The targeting signals for this posttranslational import are conserved in all eukaryotes. However, this conservation does not hold true for the protein ...
Structural overview of the translocase of the mitochondrial outer ...
The TOM complex is a multi-subunit membrane protein complex composed of a β-barrel channel Tom40 and six single-pass membrane proteins.
Biogenesis of the Mitochondrial TOM Complex
All Tom proteins are also encoded by nuclear genes and synthesized as precursors in the cytosol. The channel-forming β-barrel protein Tom40 is targeted to ...