Human CD56bright NK Cells

CD56bright natural killer (NK) cells: an important NK cell subset - PMC

In sites of peripheral inflammation, CD56bright NK cells represent 40–60% of all NK cells and display an activated phenotype (CD69+). Upon stimulation by ...

Human CD56bright NK Cells: An Update - AAI Journals

In this article, we summarize recent studies about CD56 bright NK cells in health and disease and briefly discuss the current controversies surrounding them.

CD56bright natural killer (NK) cells: an important NK cell subset

Human natural killer (NK) cells can be subdivided into different populations based on the relative expression of the surface markers CD16 and CD56. The two ...

Dissecting CD56 dim human NK cells - ASH Publications

CD56 dim cells can be further fractionated into different cell subsets on the basis of their surface markers and function.

Human Circulating and Tissue-Resident CD56bright Natural Killer ...

CD56 bright NK cells outnumber CD56 dim NK cells in the human body due to the fact that they are predominant in peripheral and lymphoid tissues.

CD56 bright NK cells exhibit potent antitumor responses following IL ...

Human NK cells are identified via surface expression of CD56 and lack of CD3, and can be categorized into 2 developmentally related, but ...

Human natural killer cells: a unique innate immunoregulatory role ...

It is proposed that human CD56 bright NK cells have a unique functional role in the innate immune response as the primary source of NK cell–derived ...

The role of CD56bright NK cells in neurodegenerative disorders

In humans, as previously mentioned, NK cells can be roughly divided into CD56brightCD16− and CD56dimCD16+ NK cells (from here on referred to as ...

NK cells CD56bright and CD56dim subset cytokine loss and ...

The NK CD56bright subset is immature and predominantly secretes cytokines in response to interleukin-12 (IL-12) and IL-18. In contrast, the NK ...

Circulating CD56 bright NK cells inversely correlate with survival of ...

The roles of NK cells in human melanoma remain only partially understood. We characterized NK cells from peripheral blood ex vivo by flow ...

Human Hepatic CD56bright NK Cells Display a Tissue ... - Frontiers

Our results highlight a role for donor liver NK cells in regulating allogenic CD8 + T cell activation, which may be important in controlling recipient CD8 + T ...

Tissue Determinants of Human NK Cell Development, Function, and ...

In humans, NK cells (CD3−CD56+) are relatively abundant, comprising 5%–20% of lymphocytes in blood and other sites (Freud et al., 2017), and ...

Metabolic Reprogramming Supports IFN-γ Production by CD56 ...

Abstract. Human NK cells can be classified into phenotypically and functionally distinct subsets based on levels of CD56 receptor. CD56dim cells are genera.

[PDF] CD56bright natural killer cells are present in human lymph ...

It is demonstrated that CD56(bright) NK cells are present in human lymph nodes and that endogenous T cell-derived IL-2, acting through the NK ...

CD56bright natural killer cells preferentially kill proliferating CD4+ T ...

Abstract. Human CD56br natural killer (NK) cells represent a small subset of CD56+ NK cells in circulation and are largely tissue-resident. The frequency a.

The CD56bright CD62L+ NKG2A+ immature cell subset is ... - bioRxiv

Here we found that the dominant cell subset in human CIML NK cells are immature CD56bright CD62L+cells, and they were selectively expanded CD56 ...

Human CD56bright NK Cells: An Update. - Abstract - Europe PMC

Human NK cells can be subdivided into various subsets based on the relative expression of CD16 and CD56. In particular, CD56(bright)CD16(-/dim) NK cells are ...

Human CD56bright NK cells: an update | Request PDF

... CD56 (bright) NK cells, which are considered to be efficient cytokine producers with immunoregulatory properties, can also become cytotoxic ...

Tissue‐resident Eomeshi T‐betlo CD56bright NK cells with reduced ...

CD56bright NK cells, which are enriched in adult human liver, are phenotypically and functionally distinct from peripheral blood.

Transcriptome analysis reveals similarities between human blood CD3

... human CD56bright cells, by gene set enrichment analysis. Conversely, the signature genes of mouse NK cells are enriched in human CD56dim cells.