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Human Platelet Antigen


human platelet antigens (HPA) - Lifeblood

Platelets express both platelet specific antigens such as human platelet antigens (HPA) and antigens which are shared with other cells such as ABO and HLA ...

Human Platelet Antigen (HPA) Database - Versiti

This database serves as the principal site for cataloging the current list of human platelet allo-antigens (HPA).

Human Platelet Antigen - an overview | ScienceDirect Topics

Human platelet antigens (HPA) are platelet specific antigens that reside on surface membrane glycoproteins.

Human platelet antigen - Wikipedia

Human platelet antigen ... Human platelet antigens (HPA) are polymorphisms in platelet antigens. These can stimulate production of alloantibodies (that is, ...

Molecular insight into human platelet antigens: structural and ...

Human platelet antigens (HPAs) are polymorphisms in platelet membrane glycoproteins (GPs) that can stimulate production of alloantibodies once exposed to ...

Platelet Antigen Genotyping Panel | Test Fact Sheet - ARUP Consult

Human platelet antigen (HPA) genotyping is used for fetal or neonatal testing following detection of unexplained intracranial hemorrhage (ICH) or ...

Human platelet antigens - 2013 - PubMed

To date, 33 human platelet alloantigens (HPAs) have been identified on six functionally important platelet glycoprotein (GP) complexes and have been ...

Platelet antigens and antibodies in pregnancy - NET

What is a platelet antigen? Every platelet has natural proteins on its surface and incorporated into these are the Human Platelet Antigens (HPA). As of 2013 ...

Human platelet antigen 1-6, 9 and 15 in the Iranian population

Human platelet antigens (HPAs) are membranous glycoproteins considered as alloantigens due to their polymorphisms.

Thrombocyte Antigen - an overview | ScienceDirect Topics

Human platelet antigens (HPAs) are alloantigens expressed on the platelet membrane. From: Clinica Chimica Acta, 2018.

Anti-human platelet antigen (HPA)-1a antibodies may affect ...

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a bleeding disorder caused by maternal antibodies against paternal human platelet ...

Natural history of human platelet antigen 1a-alloimmunised ...

We aimed to assess the incidence of clinically detectable FNAIT among pregnancies in human platelet antigen-1a (HPA-1a)-immunised women.

Human platelet antigens – 2013 - Curtis - 2014 - Wiley Online Library

33 human platelet alloantigens (HPAs) have been identified on six functionally important platelet glycoprotein (GP) complexes and have been implicated in ...

Generation of human antibodies targeting human platelet antigen ...

We have developed an efficient method to isolate HPA-1a-specific B-cells from maternal serum and generated two HPA-1a-specific monoclonal antibodies.

Association of the human platelet antigens polymorphisms with ...

This is the first study that shows the association between polymorphisms of HPA-1 to -5 and -15 and the PLT count in patients with COVID-19, making this study ...

Characterization of a Human Platelet Antigen-1a–Specific ...

Integrin αIIbβ3, which harbors HPA-1a, is the fibrinogen receptor on platelets and plays a critical role in platelet aggregation, which is central in hemostasis ...

Chapter 18: Platelet immunology - JPAC

There are several human platelet antigen (HPA) genotyping and phenotyping techniques. ... Any subsequent additions can be found in the Human Platelet Antigen.

T cell responses to human platelet antigen–1a involve a ... - JCI Insight

In most cases the alloantigen is formed by a single amino acid, integrin β3 Leu33, referred to as human platelet antigen–1a (HPA-1a). Production ...

Human Platelet Antigen 1 Genotype | Test Detail | Quest Diagnostics

Human Platelet Antigen 1 Genotype - Human Platelet Antigen (HPA) polymorphism can lead to alloimmunization that clinically can manifest as neonatal ...

Human Leukocyte and Platelet Antigens | Williams Hematology, 9e

The human leukocyte antigens (HLAs) are highly polymorphic glycoproteins encoded by a region of genes known as the major histocompatibility complex (MHC)