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Human in vitro spermatogenesis as a regenerative therapy


Human in vitro spermatogenesis as a regenerative therapy - Nature

Spermatogenesis includes a complex and highly regulated series of steps required for the production of mature, motile sperm. Efforts to recreate ...

Human in vitro spermatogenesis as a regenerative therapy - PubMed

Spermatogenesis involves precise temporal and spatial gene expression and cell signalling to reach a coordinated balance between ...

(PDF) Human in vitro spermatogenesis as a regenerative therapy

PDF | Spermatogenesis involves precise temporal and spatial gene expression and cell signalling to reach a coordinated balance between ...

Human in vitro spermatogenesis as a regenerative therapy - Abstract

Multiple approaches to study human in vitro spermatogenesis have been proposed, but technical and ethical obstacles have limited the ability to complete ...

Advances in human In vitro spermatogenesis: A review - PubMed

Recent advances surrounding in vitro spermatogenesis (IVS) have shown potential in creating a new paradigm of regenerative medicine in the ...

The Evolutionary Route of in vitro Human Spermatogenesis

However, there is no effective treatment option for patients with germ cell aplasia or spermatogenic arrest in the earlier development than the ...

Human in vitro spermatogenesis as a regenerative therapy

Article on Human in vitro spermatogenesis as a regenerative therapy - where do we stand?, published in Nature Reviews Urology 20 on ...

Human in vitro spermatogenesis as a regenerative therapy

Spermatogenesis involves precise temporal and spatial gene expression and cell signalling to reach a coordinated balance between self-renewal and ...

Recent Developments in In Vitro Spermatogenesis and Future ...

In vitro spermatogenesis is a crucial research area due to its potential in treating male infertility by artificially inducing sperm maturation outside the body ...

In vitro spermatogenesis: In search of fully defined conditions

And finally, in vitro spermatogenesis could be used to treat male infertility but only after comprehensive analysis of human haploid cells generated in vitro as ...

Advances of three-dimensional (3D) culture systems for in vitro ...

Also in vitro proliferation and differentiation of SSCs from infertile males may help infertility treatment due to stage-specific spermatogenic ...

Human in vitro spermatogenesis from pluripotent stem cells

Depending on the cell potency, several methods have been described to obtain in vitro spermatogenesis, and all seem promising for generating stem cell-derived ...

Progress and future prospect of in vitro spermatogenesis | Oncotarget

In vitro production of haploid male germ cell is a powerful tool, not only for the treatment of infertility including oligozoospermic or ...

In vitro Spermatogenesis and Its Potential Clinical Implication for ...

Among these strategies, approaches employing germ cell or testicular tissue transplantation have provided options for maturing SSCs and more advanced germ cells ...

In vitro spermatogenesis: A century‐long research journey, still half ...

The research of human in vitro spermatogenesis by the organ culture method was first performed by Steinberger16 (Figure 2). They reported that ...

Generation of rat offspring using spermatids produced through in ...

An in vitro spermatogenesis method using mouse testicular tissue to produce fertile sperm was established more than a decade ago.

Spermatogonial stem cell technologies: applications from human ...

Proposed pipelines to use these SSCs include autologous transplantation post-recovery (likely following a period of in vitro SSC expansion), autologous grafting ...

Spermatogonial Stem Cells for In Vitro Spermatogenesis and In Vivo ...

The recent progress in the use of SSCs for IVS and potential in vivo applications for the restoration of fertility are outlined. Spermatogonial stem cells ...

Spermatogonial Stem Cells for In Vitro Spermatogenesis and In Vivo ...

Successful in vitro production of human haploid male germ cells will foster hopes of preserving the fertility potential of prepubertal cancer patients who ...

The applications and recovery outcome of spermatogonia stem cells ...

These properties make spermatogonial stem cells an appropriate source for use in regenerative medicine. Spermatogonial stem cells considered as an alternative ...